Disseminated superficial actinic porokeratosis

Panta Rouhani, Max Fischer, Shane Meehan, Miriam Keltz Pomeranz

Research output: Contribution to journalArticlepeer-review

Abstract

Disseminated superficial actinic porokeratosis, which was described in 1966, is characterized by small, atrophic patches with distinctive keratin rims that occur on sun-exposed areas of the extremities, shoulders, and back. The diagnosis is based on the histopathologic finding of a cornoid lamella, absence of a granular layer, and often a thin epidermis. It is associated with exposure to ultraviolet radiation. Gene studies suggest a pathway defect in which several mutations in keratinocyte proliferation and differentiation lead to development of porokeratosis.

Original languageEnglish (US)
Number of pages1
JournalDermatology Online Journal
Volume18
Issue number12
StatePublished - Dec 1 2012

ASJC Scopus subject areas

  • Dermatology

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