Disseminated superficial actinic porokeratosis

Panta Rouhani, Max Fischer, Shane Meehan, Miriam Keltz Pomeranz

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Abstract

Disseminated superficial actinic porokeratosis, which was described in 1966, is characterized by small, atrophic patches with distinctive keratin rims that occur on sun-exposed areas of the extremities, shoulders, and back. The diagnosis is based on the histopathologic finding of a cornoid lamella, absence of a granular layer, and often a thin epidermis. It is associated with exposure to ultraviolet radiation. Gene studies suggest a pathway defect in which several mutations in keratinocyte proliferation and differentiation lead to development of porokeratosis.

Original languageEnglish (US)
Number of pages1
JournalDermatology Online Journal
Volume18
Issue number12
StatePublished - Dec 1 2012

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ASJC Scopus subject areas

  • Dermatology

Cite this

Rouhani, P., Fischer, M., Meehan, S., & Pomeranz, M. K. (2012). Disseminated superficial actinic porokeratosis. Dermatology Online Journal, 18(12).