Dissecting static and dynamic functional connectivity: Example from the autism spectrum

Tonya White, Vince D. Calhoun

Research output: Contribution to journalArticle

Abstract

The ability to measure the intrinsic functional architecture of the brain has grown exponentially over the last 2 decades. Measures of intrinsic connectivity within the brain, typically measured using resting-state functional magnetic resonance imaging (MRI), have evolved from primarily “static” approaches, to include dynamic measures of functional connectivity. Measures of dynamic functional connectivity expand the assumptions to allow brain regions to have temporally different patterns of communication between different regions. That is, connections within the brain can differentially fire between different regions at different times, and these differences can be quantified. Applying approaches that measure the dynamic characteristics of functional brain connectivity have been fruitful in identifying differences during brain development and psychopathology. We provide a brief overview of static and dynamic measures of functional connectivity and illustrate the synergy in applying these approaches to identify both age-related differences in children and differences between typically developing children and children with autistic symptoms.

Original languageEnglish (US)
JournalJournal of Experimental Neuroscience
Volume13
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Fingerprint

Autistic Disorder
Brain
Aptitude
Psychopathology
Communication
Magnetic Resonance Imaging

Keywords

  • Autism spectrum disorders
  • Children
  • Development
  • Neurodevelopment
  • Resting-state functional magnetic resonance imaging

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

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