Disorders of the parathyroid gland

Andrew Arnold, Michael A. Levine

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The parathyroid glands play a crucial role in maintaining nor mal calcium homeostasis, primarily through their regulated secretion of parathyroid hormone. A variety of congenital and acquired causes of diminished parathyroid function exist, including developmental abnormalities and defective parathyroid hormone synthesis or release, and the genetic basis for many of these is known. Primary disorders of parathyroid hyperfunction, mostly owing to parathyroid gland tumors, can be familial or sporadic. Molecular pathogenetic insights into these disorders are substantial, and have been exploited for clinical management.

Original languageEnglish (US)
Title of host publicationPrinciples of Molecular Medicine
PublisherHumana Press
Pages357-364
Number of pages8
ISBN (Print)9781588292025
DOIs
StatePublished - 2006
Externally publishedYes

Keywords

  • Calcium receptor
  • cyclin D1
  • GCMB
  • HRPT2
  • hyperparathyroidism
  • hypoparathyroidism
  • MEN1
  • parathyroid
  • parathyroid adenoma
  • parathyroid carcinoma
  • PTH

ASJC Scopus subject areas

  • Medicine(all)

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