Discrete decoding based ultrafast multidimensional nuclear magnetic resonance spectroscopy

Zhiliang Wei, Liangjie Lin, Qimiao Ye, Jing Li, Shuhui Cai, Zhong Chen

Research output: Contribution to journalArticle

Abstract

The three-dimensional (3D) nuclear magnetic resonance (NMR) spectroscopy constitutes an important and powerful tool in analyzing chemical and biological systems. However, the abundant 3D information arrives at the expense of long acquisition times lasting hours or even days. Therefore, there has been a continuous interest in developing techniques to accelerate recordings of 3D NMR spectra, among which the ultrafast spatiotemporal encoding technique supplies impressive acquisition speed by compressing a multidimensional spectrum in a single scan. However, it tends to suffer from tradeoffs among spectral widths in different dimensions, which deteriorates in cases of NMR spectroscopy with more dimensions. In this study, the discrete decoding is proposed to liberate the ultrafast technique from tradeoffs among spectral widths in different dimensions by focusing decoding on signal-bearing sites. For verifying its feasibility and effectiveness, we utilized the method to generate two different types of 3D spectra. The proposed method is also applicable to cases with more than three dimensions, which, based on the experimental results, may widen applications of the ultrafast technique.

Original languageEnglish (US)
Article number024201
JournalJournal of Chemical Physics
Volume143
Issue number2
DOIs
StatePublished - Jul 14 2015
Externally publishedYes

Fingerprint

magnetic resonance spectroscopy
decoding
Nuclear magnetic resonance spectroscopy
Decoding
Bearings (structural)
nuclear magnetic resonance
Biological systems
tradeoffs
acquisition
Nuclear magnetic resonance
compressing
coding
recording

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

Discrete decoding based ultrafast multidimensional nuclear magnetic resonance spectroscopy. / Wei, Zhiliang; Lin, Liangjie; Ye, Qimiao; Li, Jing; Cai, Shuhui; Chen, Zhong.

In: Journal of Chemical Physics, Vol. 143, No. 2, 024201, 14.07.2015.

Research output: Contribution to journalArticle

Wei, Zhiliang ; Lin, Liangjie ; Ye, Qimiao ; Li, Jing ; Cai, Shuhui ; Chen, Zhong. / Discrete decoding based ultrafast multidimensional nuclear magnetic resonance spectroscopy. In: Journal of Chemical Physics. 2015 ; Vol. 143, No. 2.
@article{6baeae27500f42dfb7aef659a306955f,
title = "Discrete decoding based ultrafast multidimensional nuclear magnetic resonance spectroscopy",
abstract = "The three-dimensional (3D) nuclear magnetic resonance (NMR) spectroscopy constitutes an important and powerful tool in analyzing chemical and biological systems. However, the abundant 3D information arrives at the expense of long acquisition times lasting hours or even days. Therefore, there has been a continuous interest in developing techniques to accelerate recordings of 3D NMR spectra, among which the ultrafast spatiotemporal encoding technique supplies impressive acquisition speed by compressing a multidimensional spectrum in a single scan. However, it tends to suffer from tradeoffs among spectral widths in different dimensions, which deteriorates in cases of NMR spectroscopy with more dimensions. In this study, the discrete decoding is proposed to liberate the ultrafast technique from tradeoffs among spectral widths in different dimensions by focusing decoding on signal-bearing sites. For verifying its feasibility and effectiveness, we utilized the method to generate two different types of 3D spectra. The proposed method is also applicable to cases with more than three dimensions, which, based on the experimental results, may widen applications of the ultrafast technique.",
author = "Zhiliang Wei and Liangjie Lin and Qimiao Ye and Jing Li and Shuhui Cai and Zhong Chen",
year = "2015",
month = "7",
day = "14",
doi = "10.1063/1.4926538",
language = "English (US)",
volume = "143",
journal = "Journal of Chemical Physics",
issn = "0021-9606",
publisher = "American Institute of Physics Publising LLC",
number = "2",

}

TY - JOUR

T1 - Discrete decoding based ultrafast multidimensional nuclear magnetic resonance spectroscopy

AU - Wei, Zhiliang

AU - Lin, Liangjie

AU - Ye, Qimiao

AU - Li, Jing

AU - Cai, Shuhui

AU - Chen, Zhong

PY - 2015/7/14

Y1 - 2015/7/14

N2 - The three-dimensional (3D) nuclear magnetic resonance (NMR) spectroscopy constitutes an important and powerful tool in analyzing chemical and biological systems. However, the abundant 3D information arrives at the expense of long acquisition times lasting hours or even days. Therefore, there has been a continuous interest in developing techniques to accelerate recordings of 3D NMR spectra, among which the ultrafast spatiotemporal encoding technique supplies impressive acquisition speed by compressing a multidimensional spectrum in a single scan. However, it tends to suffer from tradeoffs among spectral widths in different dimensions, which deteriorates in cases of NMR spectroscopy with more dimensions. In this study, the discrete decoding is proposed to liberate the ultrafast technique from tradeoffs among spectral widths in different dimensions by focusing decoding on signal-bearing sites. For verifying its feasibility and effectiveness, we utilized the method to generate two different types of 3D spectra. The proposed method is also applicable to cases with more than three dimensions, which, based on the experimental results, may widen applications of the ultrafast technique.

AB - The three-dimensional (3D) nuclear magnetic resonance (NMR) spectroscopy constitutes an important and powerful tool in analyzing chemical and biological systems. However, the abundant 3D information arrives at the expense of long acquisition times lasting hours or even days. Therefore, there has been a continuous interest in developing techniques to accelerate recordings of 3D NMR spectra, among which the ultrafast spatiotemporal encoding technique supplies impressive acquisition speed by compressing a multidimensional spectrum in a single scan. However, it tends to suffer from tradeoffs among spectral widths in different dimensions, which deteriorates in cases of NMR spectroscopy with more dimensions. In this study, the discrete decoding is proposed to liberate the ultrafast technique from tradeoffs among spectral widths in different dimensions by focusing decoding on signal-bearing sites. For verifying its feasibility and effectiveness, we utilized the method to generate two different types of 3D spectra. The proposed method is also applicable to cases with more than three dimensions, which, based on the experimental results, may widen applications of the ultrafast technique.

UR - http://www.scopus.com/inward/record.url?scp=84936884509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84936884509&partnerID=8YFLogxK

U2 - 10.1063/1.4926538

DO - 10.1063/1.4926538

M3 - Article

AN - SCOPUS:84936884509

VL - 143

JO - Journal of Chemical Physics

JF - Journal of Chemical Physics

SN - 0021-9606

IS - 2

M1 - 024201

ER -