Discrepant amplification results during the development of an assay leads to reclassification of two AIDS reagent repository HIV-2 isolates as HIV-1

Agriculture & Biology

• Human immunodeficiency virus 2 100%
• Human immunodeficiency virus 1 76%
• taxonomic revisions 68%
• assays 33%
• RNA 10%
• RNA-directed DNA polymerase 9%
• testing 9%
• immunoassays 8%
• cross reaction 7%
• reverse transcriptase polymerase chain reaction 6%
• proteinases 5%
• antigens 5%
• sequence analysis 5%
• viruses 5%
• phylogeny 4%
• sampling 2%

Medicine & Life Sciences

• HIV-2 80%
• HIV-1 54%
• Acquired Immunodeficiency Syndrome 52%
• National Institute of Allergy and Infectious Diseases (U.S.) 24%
• Centers for Disease Control and Prevention (U.S.) 16%
• HIV Core Protein p24 12%
• RNA-Directed DNA Polymerase 9%
• Molecular Pathology 8%
• Viral RNA 8%
• Sequence Analysis 7%
• Peptide Hydrolases 6%
• RNA 5%
• Viruses 5%
• Costs and Cost Analysis 4%
• Polymerase Chain Reaction 4%

Chemical Compounds

• Antigen 52%