Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kβ inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers

Victor Certal, Frank Halley, Angela Virone-Oddos, Cécile Delorme, Andreas Karlsson, Alexey Rak, Fabienne Thompson, Bruno Filoche-Rommé, Youssef El-Ahmad, Jean Christophe Carry, Pierre Yves Abecassis, Pascale Lejeune, Loic Vincent, Hélène Bonnevaux, Jean Paul Nicolas, Thomas Bertrand, Jean Pierre Marquette, Nadine Michot, Tsiala Benard, Peter BelowIsabelle Vade, Fabienne Chatreaux, Gilles Lebourg, Fabienne Pilorge, Odile Angouillant-Boniface, Audrey Louboutin, Christoph Lengauer, Laurent Schio

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