Discovering translational biomarkers in neurodevelopmental disorders

Mustafa Sahin, Stephanie R. Jones, John A. Sweeney, Elizabeth Berry-Kravis, Barry W. Connors, Joshua B. Ewen, Adam L. Hartman, April R. Levin, William Z. Potter, Laura A. Mamounas

Research output: Contribution to journalArticle

Abstract

Investment in drug development for neurodevelopmental disorders has suffered from recent failures in clinical trials that were based on promising preclinical findings. Here, we discuss development and validation of translational biomarkers of neurodevelopmental disorders that can enable more informative clinical experiments and translational success in these diseases.

Original languageEnglish (US)
Pages (from-to)235-236
Number of pages2
JournalNature Reviews Drug Discovery
Volume18
DOIs
StatePublished - Jan 1 2019

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ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

Cite this

Sahin, M., Jones, S. R., Sweeney, J. A., Berry-Kravis, E., Connors, B. W., Ewen, J. B., Hartman, A. L., Levin, A. R., Potter, W. Z., & Mamounas, L. A. (2019). Discovering translational biomarkers in neurodevelopmental disorders. Nature Reviews Drug Discovery, 18, 235-236. https://doi.org/10.1038/d41573-018-00010-7