Discordance in diagnoses and treatment of psychiatric disorders in children and adolescents with 22q11.2 deletion syndrome

Andrea S. Young, Vandana Shashi, Kelly Schoch, Thomas Kwapil, Stephen R. Hooper

Research output: Contribution to journalArticle

Abstract

This study examines the rate of utilization of mental health services in children and adolescents with 22q11.2DS relative to their remarkably high rate of psychiatric disorders and behavior problems. Seventy-two children and adolescents with 22q11.2DS were participants; their parents completed the Diagnostic Interview Schedule for Children (DISC) and the Child Behavior Checklist (CBCL). The results indicated that 22q11.2DS children and adolescents have higher rates of psychopathology than the general pediatric population, with ADHD and anxiety disorders being the most common. However, among youth with 22q11.2DS, those with psychopathology are often no more likely to receive either pharmacological or non-pharmacological mental health care than those without a given psychiatric diagnosis. Thus, although psychopathology is fairly common in this sample, many children with 22q11.2DS may not be receiving needed psychiatric care. These results have significant implications for these children and their families, as well as for the health care providers who treat them. In particular, the results may suggest a need for careful screening of psychiatric disorders that are likely to affect this population, as well as making appropriate treatment recommendations to remedy childhood mental health problems. Since these children face an extraordinarily high risk of psychoses in late adolescence/adulthood, treatment of childhood psychopathology could be crucial in mitigating the risk/consequences of major psychiatric illnesses in later life.

Original languageEnglish (US)
Pages (from-to)119-124
Number of pages6
JournalAsian Journal of Psychiatry
Volume4
Issue number2
DOIs
StatePublished - Jun 1 2011
Externally publishedYes

Keywords

  • 22q11.2DS
  • Children/adolescents
  • DiGeorge syndrome
  • Psychopathology
  • Service utilization
  • Velocardiofacial syndrome

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

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