Direct visualization of vesicle-bilayer complexes by atomic force microscopy

Sanjay Kumar, Jan H. Hoh

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Atomic force microscope (AFM) images of vesicle-bilayer complexes formed by adsorbing small unilamellar devices (SUVs) onto mica to form a continuous membrane and allowing excess vesicles to settle onto the membrane were obtained. Depth measurements showed the formation of a continuous supported membrane. Mechanical and structural evidence indicate that the adsorbed structures truly are individual lipid vesicles. The morphology of the adsorbed structures was found to be a function of lipid composition.

Original languageEnglish (US)
Pages (from-to)9936-9940
Number of pages5
Issue number25
StatePublished - Dec 12 2000

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry


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