Dipole lattice membrane model for protein calculations

Alan Grossfield, Jonathan Sachs, Thomas B Woolf

Research output: Contribution to journalArticle

Abstract

A dipole lattice model for lipid membranes and their interactions with peptides is presented. It uses the Langevin dipole method to calculate electrostatic interactions in the heterogenous membrane environment. A series of test cases are presented, including spherical charges, dipoles, side chain analogs, and helical peptides. The model consistently produces qualitatively correct results. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)211-223
Number of pages13
JournalProteins
Volume41
Issue number2
DOIs
StatePublished - Nov 1 2000

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Membrane Proteins
Membranes
Peptides
Membrane Lipids
Coulomb interactions
Static Electricity
Proteins

ASJC Scopus subject areas

  • Genetics
  • Structural Biology
  • Biochemistry

Cite this

Dipole lattice membrane model for protein calculations. / Grossfield, Alan; Sachs, Jonathan; Woolf, Thomas B.

In: Proteins, Vol. 41, No. 2, 01.11.2000, p. 211-223.

Research output: Contribution to journalArticle

Grossfield, Alan ; Sachs, Jonathan ; Woolf, Thomas B. / Dipole lattice membrane model for protein calculations. In: Proteins. 2000 ; Vol. 41, No. 2. pp. 211-223.
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