Diminished adherence of sickle erythrocytes to cultured vascular endothelium by piracetam

Robert M. Nalbandian; Raymond L. Henry; C. Lynne Burek; Clement A. Diglio; Arnold I. Goldman; Gregory W. Taylor; William H. Hoffman

doi:10.1002/ajh.2830150206

Diminished adherence of sickle erythrocytes to cultured vascular endothelium by piracetam

Robert M. Nalbandian, Raymond L. Henry, C. Lynne Burek, Clement A. Diglio, Arnold I. Goldman, Gregory W. Taylor, William H. Hoffman

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Erythrocytes from both normal and sickle cell donors were incubated on a bed of cultured rat vascular endothelial cells. Although the adherence of the erythrocytes to the endothelial cells was equivalent for both classes of donor, addition of 1.5 mM piracetam significantly decreased this adherence regardless of donor.

Original language	English (US)
Pages (from-to)	147-151
Number of pages	5
Journal	American journal of hematology
Volume	15
Issue number	2
DOIs	https://doi.org/10.1002/ajh.2830150206
State	Published - Sep 1983
Externally published	Yes

Keywords

cell adherence
endothelial cell culture
erythrocytes
piracetam
sickle cell disease

ASJC Scopus subject areas

Hematology

Access to Document

10.1002/ajh.2830150206

Cite this

@article{c6364a6ac7e248429027e3b818591641,

title = "Diminished adherence of sickle erythrocytes to cultured vascular endothelium by piracetam",

abstract = "Erythrocytes from both normal and sickle cell donors were incubated on a bed of cultured rat vascular endothelial cells. Although the adherence of the erythrocytes to the endothelial cells was equivalent for both classes of donor, addition of 1.5 mM piracetam significantly decreased this adherence regardless of donor.",

keywords = "cell adherence, endothelial cell culture, erythrocytes, piracetam, sickle cell disease",

author = "Nalbandian, {Robert M.} and Henry, {Raymond L.} and Burek, {C. Lynne} and Diglio, {Clement A.} and Goldman, {Arnold I.} and Taylor, {Gregory W.} and Hoffman, {William H.}",

year = "1983",

month = sep,

doi = "10.1002/ajh.2830150206",

language = "English (US)",

volume = "15",

pages = "147--151",

journal = "American journal of hematology",

issn = "0361-8609",

publisher = "Wiley-Liss Inc.",

number = "2",

}

TY - JOUR

T1 - Diminished adherence of sickle erythrocytes to cultured vascular endothelium by piracetam

AU - Nalbandian, Robert M.

AU - Henry, Raymond L.

AU - Burek, C. Lynne

AU - Diglio, Clement A.

AU - Goldman, Arnold I.

AU - Taylor, Gregory W.

AU - Hoffman, William H.

PY - 1983/9

Y1 - 1983/9

N2 - Erythrocytes from both normal and sickle cell donors were incubated on a bed of cultured rat vascular endothelial cells. Although the adherence of the erythrocytes to the endothelial cells was equivalent for both classes of donor, addition of 1.5 mM piracetam significantly decreased this adherence regardless of donor.

AB - Erythrocytes from both normal and sickle cell donors were incubated on a bed of cultured rat vascular endothelial cells. Although the adherence of the erythrocytes to the endothelial cells was equivalent for both classes of donor, addition of 1.5 mM piracetam significantly decreased this adherence regardless of donor.

KW - cell adherence

KW - endothelial cell culture

KW - erythrocytes

KW - piracetam

KW - sickle cell disease

UR - http://www.scopus.com/inward/record.url?scp=0020609718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020609718&partnerID=8YFLogxK

U2 - 10.1002/ajh.2830150206

DO - 10.1002/ajh.2830150206

M3 - Article

C2 - 6613985

AN - SCOPUS:0020609718

SN - 0361-8609

VL - 15

SP - 147

EP - 151

JO - American journal of hematology

JF - American journal of hematology

IS - 2

ER -

Diminished adherence of sickle erythrocytes to cultured vascular endothelium by piracetam

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this