Diffusion tensor imaging and fiber tractography in brain malformations

Andrea Poretti, Avner Meoded, Andrea Rossi, Charles Raybaud, Thierry A.G.M. Huisman

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and quantitative information about the micro-architecture of white matter. DTI and its post-processing tool fiber tractography (FT) have been increasingly used in the last decade to investigate the microstructural neuroarchitecture of brain malformations. This article aims to review the use of DTI and FT in the evaluation of a variety of common, well-described brain malformations, in particular by pointing out the additional information that DTI and FT renders compared with conventional MR sequences. In addition, the relevant existing literature is summarized.

Original languageEnglish (US)
Pages (from-to)28-54
Number of pages27
JournalPediatric radiology
Issue number1
StatePublished - Jan 2013


  • Brain malformations
  • Children
  • Diffusion tensor imaging
  • Fiber tractography
  • MRI

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging


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