Differential Patterns of Memory Loss Among Patients With Alzheimer's Disease, Huntington's Disease, and Alcoholic Korsakoff's Syndrome

Mark B. Moss, Marilyn S. Albert, Nelson Butters, Melanie Payne

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with Huntington's disease (HD), alcoholic Korsakoff's syndrome (KS), and Alzheimer's disease (AD) were compared with normal control subjects on a task designed to assess recognition memory for different classes of stimuli: spatial, verbal, color, pattern, and facial. In addition, recall of verbal stimuli was assessed at two delay intervals. On recognition testing, AD and KS patients were impaired on each of the five stimulus conditions. However, HD patients, though impaired on four of the recognition conditions, were unimpaired when verbal stimuli were used. On recall testing, the AD, HD, and KS groups were equally impaired at the shorter delay (15 s). However, at the longer delay (two minutes), the KS and HD patients, though still impaired relative to the normal control group, performed significantly better than the AD group.

Original languageEnglish (US)
Pages (from-to)239-246
Number of pages8
JournalArchives of neurology
Volume43
Issue number3
DOIs
StatePublished - Mar 1986
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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