TY - CHAP
T1 - Different tumor microenvironments lead to different metabolic phenotypes
AU - Antonio, Marjorie Justine
AU - Le, Anne
N1 - Publisher Copyright:
© 2018, Springer International Publishing AG, part of Springer Nature.
PY - 2018
Y1 - 2018
N2 - Cancer cells adapt to changes in nutrient and oxygen availability by adopting alternative metabolic pathways.Fatty acid oxidation in cancer cells is a survival mechanism of action to glucose deprivation.Lipid scavenging is utilized to enable cancer cells to survive periods of tumor regression.Distinct, and often complementary, metabolic processes operate concurrently within a single tumor.
AB - Cancer cells adapt to changes in nutrient and oxygen availability by adopting alternative metabolic pathways.Fatty acid oxidation in cancer cells is a survival mechanism of action to glucose deprivation.Lipid scavenging is utilized to enable cancer cells to survive periods of tumor regression.Distinct, and often complementary, metabolic processes operate concurrently within a single tumor.
KW - Fatty acid oxidation
KW - Heterogeneity of cancer
KW - Metabolic phenotypes
KW - Metabolic processes
KW - Tumor microenvironments
UR - http://www.scopus.com/inward/record.url?scp=85049337608&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049337608&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-77736-8_9
DO - 10.1007/978-3-319-77736-8_9
M3 - Chapter
C2 - 29946780
AN - SCOPUS:85049337608
T3 - Advances in Experimental Medicine and Biology
SP - 119
EP - 129
BT - Advances in Experimental Medicine and Biology
PB - Springer New York LLC
ER -