The lowest cell number in the normal marrow transplant, which allows the cure of W/Wv anemia was found to be between 104 and 105. This exceeds by several times the lowest cell number necessary for the haemopoietic colony formation. Therefore, either the colony forming cell is not the haemopoietic stem cell but rather its progeny, or this cell requires an aid from some other cells to exert its activity.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)