Different generators in human temporal-parasylvian cortex account for subdural laser-evoked potentials, auditory-evoked potentials, and event- related potentials

Frederick Lenz, Gregory Krauss, R. D. Treede, J. I. Lee, Dana F Boatman, Nathan E Crone, R. Minahan, J. Port, M. Rios

Research output: Contribution to journalArticle

Abstract

In order to localize cortical areas mediating pain we now report subdural cortical potentials evoked by auditory stimulation (auditory-evoked potentials - AEPs) and by cutaneous stimulation with a laser (laser-evoked potentials - LEPs). Stimulation with the laser evokes a pure pain sensation by selective activation of nociceptors. LEPs were maximal over the inferior aspect of the central sulcus and had the same polarity on either side of the sylvian fissure. AEPs were maximal posterior to the LEP maximum and had opposite polarity on opposite sides of the sylvian fissure, consistent with the location of a known generator in the temporal operculum. Auditory P3 (event-related) potentials were maximal over the temporal base. These findings demonstrate that the LEP generator is not in secondary somatosensory cortex on the parietal operculum and is different from the P3 generator. (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish (US)
Pages (from-to)153-156
Number of pages4
JournalNeuroscience Letters
Volume279
Issue number3
DOIs
StatePublished - Feb 4 2000

Fingerprint

Auditory Evoked Potentials
Temporal Lobe
Evoked Potentials
Lasers
P300 Event-Related Potentials
Acoustic Stimulation
Pain
Nociceptors
Somatosensory Cortex
Skin
Laser-Evoked Potentials

Keywords

  • Auditory-evoked potentials
  • Laser-evoked potentials
  • P3
  • Pain
  • Parasylvian cortex
  • Temporal lobe

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

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title = "Different generators in human temporal-parasylvian cortex account for subdural laser-evoked potentials, auditory-evoked potentials, and event- related potentials",
abstract = "In order to localize cortical areas mediating pain we now report subdural cortical potentials evoked by auditory stimulation (auditory-evoked potentials - AEPs) and by cutaneous stimulation with a laser (laser-evoked potentials - LEPs). Stimulation with the laser evokes a pure pain sensation by selective activation of nociceptors. LEPs were maximal over the inferior aspect of the central sulcus and had the same polarity on either side of the sylvian fissure. AEPs were maximal posterior to the LEP maximum and had opposite polarity on opposite sides of the sylvian fissure, consistent with the location of a known generator in the temporal operculum. Auditory P3 (event-related) potentials were maximal over the temporal base. These findings demonstrate that the LEP generator is not in secondary somatosensory cortex on the parietal operculum and is different from the P3 generator. (C) 2000 Elsevier Science Ireland Ltd.",
keywords = "Auditory-evoked potentials, Laser-evoked potentials, P3, Pain, Parasylvian cortex, Temporal lobe",
author = "Frederick Lenz and Gregory Krauss and Treede, {R. D.} and Lee, {J. I.} and Boatman, {Dana F} and Crone, {Nathan E} and R. Minahan and J. Port and M. Rios",
year = "2000",
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doi = "10.1016/S0304-3940(99)00986-6",
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TY - JOUR

T1 - Different generators in human temporal-parasylvian cortex account for subdural laser-evoked potentials, auditory-evoked potentials, and event- related potentials

AU - Lenz, Frederick

AU - Krauss, Gregory

AU - Treede, R. D.

AU - Lee, J. I.

AU - Boatman, Dana F

AU - Crone, Nathan E

AU - Minahan, R.

AU - Port, J.

AU - Rios, M.

PY - 2000/2/4

Y1 - 2000/2/4

N2 - In order to localize cortical areas mediating pain we now report subdural cortical potentials evoked by auditory stimulation (auditory-evoked potentials - AEPs) and by cutaneous stimulation with a laser (laser-evoked potentials - LEPs). Stimulation with the laser evokes a pure pain sensation by selective activation of nociceptors. LEPs were maximal over the inferior aspect of the central sulcus and had the same polarity on either side of the sylvian fissure. AEPs were maximal posterior to the LEP maximum and had opposite polarity on opposite sides of the sylvian fissure, consistent with the location of a known generator in the temporal operculum. Auditory P3 (event-related) potentials were maximal over the temporal base. These findings demonstrate that the LEP generator is not in secondary somatosensory cortex on the parietal operculum and is different from the P3 generator. (C) 2000 Elsevier Science Ireland Ltd.

AB - In order to localize cortical areas mediating pain we now report subdural cortical potentials evoked by auditory stimulation (auditory-evoked potentials - AEPs) and by cutaneous stimulation with a laser (laser-evoked potentials - LEPs). Stimulation with the laser evokes a pure pain sensation by selective activation of nociceptors. LEPs were maximal over the inferior aspect of the central sulcus and had the same polarity on either side of the sylvian fissure. AEPs were maximal posterior to the LEP maximum and had opposite polarity on opposite sides of the sylvian fissure, consistent with the location of a known generator in the temporal operculum. Auditory P3 (event-related) potentials were maximal over the temporal base. These findings demonstrate that the LEP generator is not in secondary somatosensory cortex on the parietal operculum and is different from the P3 generator. (C) 2000 Elsevier Science Ireland Ltd.

KW - Auditory-evoked potentials

KW - Laser-evoked potentials

KW - P3

KW - Pain

KW - Parasylvian cortex

KW - Temporal lobe

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