Dietary therapy is the best option for refractory nonsurgical epilepsy

Elizabeth A. Felton, MacKenzie C. Cervenka

Research output: Contribution to journalArticlepeer-review

Abstract

Summary Ketogenic diet therapies for epilepsy have been described since the fifth century and published in scientific literature since the early 1900s. Since that time, the diet's popularity has waxed and waned as newer drugs and other treatments have been introduced. However, in recent years, dietary therapy for epilepsy has been increasingly accepted by physicians and desired by patients as an alternative to new drugs and neurostimulation. The introduction of less restrictive versions of the classic ketogenic diet, such as the modified Atkins diet (MAD), have led to increased numbers of adult patients with refractory epilepsy who are initiating dietary treatment. Approximately half of adults and children who start a ketogenic diet have a >50% seizure reduction, which is impressive given that these patients typically have medically refractory epilepsy. We believe that ketogenic dietary treatment is the best option for children and adults with refractory nonsurgical epilepsy due to its efficacy, rapid seizure reduction, synergistic effects with other antiseizure treatments, known and treatable side effects, potential to treat comorbid medical conditions, and worldwide availability.

Original languageEnglish (US)
Pages (from-to)1325-1329
Number of pages5
JournalEpilepsia
Volume56
Issue number9
DOIs
StatePublished - Sep 1 2015

Keywords

  • Epilepsy
  • Ketogenic
  • Modified Atkins diet

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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