Dietary Approaches to Stop Hypertension: Rationale, design, and methods

Thomas M. Vogt, Lawrence J. Appel, Eva Obarzanek, Thomas J. Moore, William M. Vollmer, Laura P. Svetkey, Frank M. Sacks, George A. Bray, Jeffrey A. Cutler, Marlene M. Windhauser, Pao Hwa Lin, Njeri M. Karanja

Research output: Contribution to journalArticlepeer-review

Abstract

Epidemiologic studies across societies have shown consistent differences in blood pressure that appear to be related to diet. Vegetarian diets are consistently associated with reduced blood pressure in observational and interventional studies, but clinical trials of individual nutrient supplements have had an inconsistent pattern of results. Dietary Approaches to Stop Hypertension (DASH) was a multicenter, randomized feeding study, designed to compare the impact on blood pressure of 3 dietary patterns. DASH was designed as a test of eating patterns rather than of individual nutrients in an effort to identify practical, palatable dietary approaches that might have a meaningful impact on reducing morbidity and mortality related to blood pressure in the general population. The objectives of this article are to present the scientific rationale for this trial, review the methods used, and discuss important design considerations and implications.

Original languageEnglish (US)
Pages (from-to)S12-S18
JournalJournal of the American Dietetic Association
Volume99
Issue number8 SUPPL.
DOIs
StatePublished - Aug 1999

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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