TY - JOUR
T1 - Diet and Respiratory Health in Children from 11 Latin American Countries
T2 - Evidence from ISAAC Phase III
AU - And The Isaac Phase Iii Latin America Group
AU - Cepeda, Alfonso Mario
AU - Thawer, Sumaiyya
AU - Boyle, Robert J.
AU - Villalba, Sara
AU - Jaller, Rodolfo
AU - Tapias, Elmy
AU - Segura, Ana María
AU - Villegas, Rodrigo
AU - Garcia-Larsen, Vanessa
N1 - Funding Information:
We are grateful to the mothers and children who took part in the study. The ISAAC Phase III study in Latin America was made possible through independent funding secured by each participant centre. We are grateful to the Coordinating Centre in New Zealand for the helpful support with the access to the data. We are indebted to Professor Majid Ezzati for his careful comments on the interpretation of the results. ARGENTINA: Carlos E Baena-Cagnani, Gustavo E Zabert, Carlos D Crisci, Maximiliano Gómez, Hugo Neffen; BOLIVIA: Rosario Pinto-Vargas; BRAZIL: Dirceu Solé, Jackeline Machado-Motta, Ricardo A Gurgel , Paulo A Camargos, Wellington G Borges, Almerinda Silva, Nelson A Rosário, Leda Solano Costa Leda de Freitas Souza, Cláudia Dutra-Bernhardt, Francisco José Passos-Soares, Mercia Lamenha, Maria do Socorro Cardoso, Antônio Ledo Aves da Cunha, Arnaldo Porto-Neto, Gilberto Bueno Fischer, Victor E Cassol, Cassia Gonzales , Karyn C Melo, Cristina A Jacob, Fabio Kuschnir, Emanuel Sarinho Murilo de Britto, Neusa Wandalsen, Antonio Carlos Pastorino; BOLIVIA: Rosario Pinto, Esther Serrate, Roberto Paz, Pitias Suárez, Oscar Gómez, Janet Aguirre; CHILE: Viviana Aguirre-Camposano, Luis Vera-Benavides, Amanda Contreras, Lidia Amarales, Pedro Aguilar, Mario A Calvo, Javier Mallol (Regional Coordinator); COLOMBIA: Alfonso M. Cepeda, Gustavo Aristizábal, Gustavo A Ordoñez; COSTA RICA: Manuel Soto-Quiroz. CUBA: Patricia Varona-Peréz, ECUADOR: César Bustos, Sergio Barba, Rocío de Janón, Mireya Rodas, Alfredo Sierra, José Ulloa,. EL SALVADOR: Margarita Figueroa-Colorado; HONDURAS: Agustin Bueso-Engelhardt; MEXICO: Manuel Baeza-Bacab, Blanca E Del Río-Navarro, Mercedes Barragán-Meijueiro, Nelly Ramírez-Chanona, Roberto García-Almaraz, Isabelle Romieu, Valente Merida-Palacio, Sandra Nora González-Díaz, Francisco J. Linares-Zapién, Sergio Romero-Tapia; NICARAGUA: José F Sánchez; PANAMA: Gherson Cukier; PARAGUAY: Jaime A. Guggiari-Chasse; PERU: Pascual Chiarella; URUGUAY: Dolores Holgado, María Cristina Lapides; VENEZUELA: Oscar Aldrey. Collaborators of the ISAAC Phase III Latin America Groups are listed in “Acknowledgement”. The authors declare that they have no conflict of interest.
Publisher Copyright:
© 2017, The Author(s).
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Background and Aim: The burden of childhood asthma and its risk factors is an important but neglected public health challenge in Latin America. We investigated the association between allergic symptoms and dietary intake in children from this region. Methods: As part of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase III, questionnaire collected dietary intake was investigated in relation to risk of parental/child reported current wheeze (primary outcome) and rhino-conjunctivitis and eczema. Per-country adjusted logistic regressions were performed, and combined effect sizes were calculated with meta-analyses. Results: 143,967 children from 11 countries had complete data. In children aged 6–7 years, current wheeze was negatively associated with higher fruit intake (adjusted odds ratio [aOR] 0.65; 95% CI 0.74, 0.97). Current rhino-conjunctivitis and eczema were statistically negatively associated with fruit intake (aOR 0.72; 95% CI 0.64, 0.82; and OR 0.64, 95% CI 0.56, 0.74, respectively). Vegetable intake was negatively associated with risk of symptoms in younger children, but these associations were attenuated in the 13–14 years old group. Fastfood/burger intake was positively associated with all three outcomes in the older children. Conclusion: A higher intake of fruits and vegetables was associated with a lower prevalence of allergic symptoms in Latin American children. Conversely, intake of fastfood was positively associated with a higher prevalence of wheeze in adolescents. Improved dietary habits in children might help reduce the epidemic of allergic symptoms in Latin America. Food interventions in asthmatic children are needed to evaluate the possible public health impact of a better diet on respiratory health.
AB - Background and Aim: The burden of childhood asthma and its risk factors is an important but neglected public health challenge in Latin America. We investigated the association between allergic symptoms and dietary intake in children from this region. Methods: As part of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase III, questionnaire collected dietary intake was investigated in relation to risk of parental/child reported current wheeze (primary outcome) and rhino-conjunctivitis and eczema. Per-country adjusted logistic regressions were performed, and combined effect sizes were calculated with meta-analyses. Results: 143,967 children from 11 countries had complete data. In children aged 6–7 years, current wheeze was negatively associated with higher fruit intake (adjusted odds ratio [aOR] 0.65; 95% CI 0.74, 0.97). Current rhino-conjunctivitis and eczema were statistically negatively associated with fruit intake (aOR 0.72; 95% CI 0.64, 0.82; and OR 0.64, 95% CI 0.56, 0.74, respectively). Vegetable intake was negatively associated with risk of symptoms in younger children, but these associations were attenuated in the 13–14 years old group. Fastfood/burger intake was positively associated with all three outcomes in the older children. Conclusion: A higher intake of fruits and vegetables was associated with a lower prevalence of allergic symptoms in Latin American children. Conversely, intake of fastfood was positively associated with a higher prevalence of wheeze in adolescents. Improved dietary habits in children might help reduce the epidemic of allergic symptoms in Latin America. Food interventions in asthmatic children are needed to evaluate the possible public health impact of a better diet on respiratory health.
KW - Asthma
KW - Children
KW - Diet
KW - Fruits
KW - ISAAC Phase III
KW - Latin America
KW - Vegetables
KW - Wheeze
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U2 - 10.1007/s00408-017-0044-z
DO - 10.1007/s00408-017-0044-z
M3 - Article
C2 - 28849295
AN - SCOPUS:85028556015
SN - 0341-2040
VL - 195
SP - 683
EP - 692
JO - Lung
JF - Lung
IS - 6
ER -