Dientamoeba fragilis masquerading as allergic colitis

Carmello Cuffari, Luc Oligny, Ernest G. Seidman

Research output: Contribution to journalArticlepeer-review


Background: Dientamoeba fragilis is a rare cause of chronic infectious diarrhea and colitis in children. Methods: Review of the clinical manifestations, diagnostic methods, and clinical course of D. fragilis infection in our hospital. Results: Eleven pediatric patients are discussed, seven of whom had a history of recent travel. Clinical manifestations of infectious diarrhea included anorexia, intermittent vomiting, abdominal pain, and diarrhea, ranging from 1 to 100 weeks in duration. Peripheral eosinophilia was present in seven patients. One patient with well-documented bovine protein allergy had intermittent episodes of diarrhea and abdominal pain, despite an appropriate elimination diet. Eosinophilic colitis documented by colonoscopy, was due to D. fragilis. Metronidazole was effective in treating five patients, and iodoquinol was effective in treating four others. Conclusions: D. fragilis should be included in the differential diagnosis of chronic diarrhea and eosinophilic colitis. The identification of this pathogen requires clinical awareness of epidemiologic risk factors and presenting complaints, as well as the laboratory staining procedures essential to its proper identification.

Original languageEnglish (US)
Pages (from-to)16-20
Number of pages5
JournalJournal of pediatric gastroenterology and nutrition
Issue number1
StatePublished - Jan 1998
Externally publishedYes


  • Allergic colitis
  • Diarrhea
  • Dientamoeba fragilis
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology


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