Dichloromethotrexate - A critical reassessment

P. J. O'Dwyer; B. Leyland-Jones; M. T. Alonso; M. Eisenberger; D. F. Hoth

doi:10.1200/JCO.1985.3.8.1148

Dichloromethotrexate - A critical reassessment

P. J. O'Dwyer, B. Leyland-Jones, M. T. Alonso, M. Eisenberger, D. F. Hoth

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We review the biochemical, pharmacologic, and clinical evidence, which indicates that dichloromethotrexate (DCMTX) may in certain circumstances display a therapeutic advantage over the parent compound methotrexate (MTX); studies are suggested to clarify the role of DCMTX in the clinic.

Original language	English (US)
Pages (from-to)	1148-1153
Number of pages	6
Journal	Journal of Clinical Oncology
Volume	3
Issue number	8
DOIs	https://doi.org/10.1200/JCO.1985.3.8.1148
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1200/JCO.1985.3.8.1148

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title = "Dichloromethotrexate - A critical reassessment",

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author = "O'Dwyer, {P. J.} and B. Leyland-Jones and Alonso, {M. T.} and M. Eisenberger and Hoth, {D. F.}",

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AU - Leyland-Jones, B.

AU - Alonso, M. T.

AU - Eisenberger, M.

AU - Hoth, D. F.

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AB - We review the biochemical, pharmacologic, and clinical evidence, which indicates that dichloromethotrexate (DCMTX) may in certain circumstances display a therapeutic advantage over the parent compound methotrexate (MTX); studies are suggested to clarify the role of DCMTX in the clinic.

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Dichloromethotrexate - A critical reassessment

Abstract

ASJC Scopus subject areas

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