TY - JOUR
T1 - Diagnostic utility of the subjective peripheral neuropathy screen in HIV-infected persons with peripheral sensory polyneuropathy
AU - Venkataramana, Anita B.
AU - Skolasky, Richard L.
AU - Creighton, Jason A.
AU - McArthur, Justin C.
PY - 2005/7/1
Y1 - 2005/7/1
N2 - A retrospective analysis of the Johns Hopkins University HIV neurology database was performed to assess the sensitivity and specificity of the Subjective Peripheral Neuropathy Screen (SPNS) for detecting HIV-associated sensory neuropathies. The SPNS, a 3-item scale that evaluates lower extremity neuropathic symptoms, was administered to 75 patients from the HIV neurology outpatient clinic. Patients graded the severity of each symptom on a scale of 1 to 10, and the sensitivity, specificity, and diagnostic efficiency of the SPNS were calculated for each symptom. The results showed that the SPNS had a sensitivity of 47%, a specificity of 83%, a positive predictive value of 70%, and a diagnostic efficacy of 67%. The SPNS appears to be a useful screening tool for HIV-associated sensory neuropathies; it has a high specificity and a good positive predictive value.
AB - A retrospective analysis of the Johns Hopkins University HIV neurology database was performed to assess the sensitivity and specificity of the Subjective Peripheral Neuropathy Screen (SPNS) for detecting HIV-associated sensory neuropathies. The SPNS, a 3-item scale that evaluates lower extremity neuropathic symptoms, was administered to 75 patients from the HIV neurology outpatient clinic. Patients graded the severity of each symptom on a scale of 1 to 10, and the sensitivity, specificity, and diagnostic efficiency of the SPNS were calculated for each symptom. The results showed that the SPNS had a sensitivity of 47%, a specificity of 83%, a positive predictive value of 70%, and a diagnostic efficacy of 67%. The SPNS appears to be a useful screening tool for HIV-associated sensory neuropathies; it has a high specificity and a good positive predictive value.
KW - Clinical trials
KW - HIV/AIDS
KW - Peripheral neuropathy
KW - Sensory neuropathies
KW - Subjective peripheral neuropathy screen
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M3 - Article
C2 - 16044575
AN - SCOPUS:22144452228
VL - 15
SP - 341-344+348-349+354
JO - AIDS Reader
JF - AIDS Reader
SN - 1053-0894
IS - 7
ER -