TY - JOUR
T1 - Diagnostic tests in ragweed-allergic asthma. A comparison of direct skin tests, leukocyte histamine release, and quantitative bronchial challenge
AU - Bruce, C. Allen
AU - Rosenthal, Richard R.
AU - Lichtenstein, Lawrence M.
AU - Norman, Philip S.
N1 - Funding Information:
Good Samaritan Hospital. by Research Grants AI 04866, AT 08270, and Al 10304 and Training from the National Institute of Allergy and Infectious Diseases of of Health, Bethesda, Md. PuMication No. 101 of the O’Neill Research for publication Aug. 23, 1973.
PY - 1974/4
Y1 - 1974/4
N2 - Thirty-six patients with a history of seasonal ragweed asthma were tested. Direct intradermal skin tests, leukocyte histamine release, and quantitative inhalation bronchial challenge correlated significantly. Data reported suggest that quantitative skin tests are as diagnostically valuable as quantitative inhalation bronchial challenge or leukocyte histamine release. Data also suggest that lung and skin mast cells and circulating basophils respond as a single population of cells to ragweed antigens.
AB - Thirty-six patients with a history of seasonal ragweed asthma were tested. Direct intradermal skin tests, leukocyte histamine release, and quantitative inhalation bronchial challenge correlated significantly. Data reported suggest that quantitative skin tests are as diagnostically valuable as quantitative inhalation bronchial challenge or leukocyte histamine release. Data also suggest that lung and skin mast cells and circulating basophils respond as a single population of cells to ragweed antigens.
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U2 - 10.1016/0091-6749(74)90085-2
DO - 10.1016/0091-6749(74)90085-2
M3 - Article
C2 - 4134207
AN - SCOPUS:0016052063
SN - 0091-6749
VL - 53
SP - 230
EP - 239
JO - The Journal of allergy and clinical immunology
JF - The Journal of allergy and clinical immunology
IS - 4
ER -