Diagnostic sensitivity of indocyanine green angiography for birdshot chorioretinopathy

Ashvini K. Reddy, Marco A. Gonzalez, Christopher R. Henry, Steven Yeh, Lucia Sobrin, Thomas A. Albini

Research output: Contribution to journalArticle

Abstract

IMPORTANCE: To describe a cohort of patients with birdshot chorioretinopathy who did not manifest birdshot lesions on clinical examination but had retinal vasculitis, low-grade to moderate vitritis, and hypocyanescent lesions on indocyanine green angiography (ICGA). OBSERVATIONS: Case series of 3 patients with mild to moderate vitritis and retinal vasculitis without definite birdshot lesions on clinical examination evaluated from January 2007 to December 2014 at 4 academic ophthalmology centers. All patients' results were positive for human leukocyte antigen-A29. All cases had hypocyanescent lesions visible on ICGA but not detectable on fluorescein angiography. CONCLUSIONS AND RELEVANCE: Patients with retinal vasculitis and low-grade vitritis with or without macular edema may have birdshot chorioretinopathy evident on ICGA before lesions are visible on clinical examination or fluorescein angiography. Expanding birdshot chorioretinopathy diagnostic criteria to include the presence of hypocyanescent lesions on ICGA could improve the sensitivity of diagnosis.

Original languageEnglish (US)
Pages (from-to)840-843
Number of pages4
JournalJAMA ophthalmology
Volume133
Issue number7
DOIs
StatePublished - Jul 1 2015

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ASJC Scopus subject areas

  • Ophthalmology

Cite this

Reddy, A. K., Gonzalez, M. A., Henry, C. R., Yeh, S., Sobrin, L., & Albini, T. A. (2015). Diagnostic sensitivity of indocyanine green angiography for birdshot chorioretinopathy. JAMA ophthalmology, 133(7), 840-843. https://doi.org/10.1001/jamaophthalmol.2015.0822