Eficacia diagnóstica del estudio de contactos de enfermos tuberculosos en un distrito urbano de alta prevalencia

Translated title of the contribution: Diagnostic efficacy of the study of contacts of tuberculosis patients in a high prevalence urban area

J. Solsona Peiró, J. A. Caylà, M. Bedia, C. Mata, J. Claveria, M. P. Estrada, S. Garcia, R. Besora, D. Roca, B. Miquel, N. Altet, J. Nadal, J. Maldonado, A. Fernández, J. Alcaide

Research output: Contribution to journalArticle

Abstract

Background. The investigation of contacts (CI) is a main objective for the control of tuberculosis (TB) after therapeutic compliance. The present study was planned to determine the diagnostic effectiveness and degree of CI implementation as well as risk factors to generate new cases in a high prevalence area (163/105). Patients and methods. An analysis was made of the available data of CI in the Barcelona district of Ciutat Vella in 1997 and 1998. The odds ratio (OR) was calculated as a measure of the association with infection and tuberculosis disease with a 95% confidence interval (CI) by logistic regression. Results. CI was made in 65.2% of patients and 100% of tuberculin-positive children. Thirty patients were diagnosed among 858 contacts of 135 tuberculosis patients (3.49%) and 8 among 318 contacts of 64 primoinfected children aged less than 15 years (2.51%). Prevalence of tuberculosis infection was 51.51% and 46.85%, respectively. The characteristics of the index case associated with new patients were drug abuse (OR: 11.16; CI: 3.0-40.9) and to be prisoner (OR: 18.7; CI: 1.5-232.9). No influence was detected regarding sputum acid-fast smears and degree of closeness except for contacts aged less than 20 years. Conclusions. CI is cost-effective in this area of high prevalence and should be performed in every TB case although priority groups are prisoners and/or drug abusers and contacts aged less than 20 years. The implementation of CI can be improved in our setting.

Original languageSpanish
Pages (from-to)412-419
Number of pages8
JournalRevista Clinica Espanola
Volume200
Issue number8
StatePublished - Aug 2000
Externally publishedYes

Fingerprint

Tuberculosis
Confidence Intervals
Prisoners
Odds Ratio
Tuberculin
Drug Users
Infection
Sputum
Substance-Related Disorders
Logistic Models
Costs and Cost Analysis
Acids

Keywords

  • Contact study
  • Diagnostic efficacy
  • Risk factors
  • Tuberculosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Solsona Peiró, J., Caylà, J. A., Bedia, M., Mata, C., Claveria, J., Estrada, M. P., ... Alcaide, J. (2000). Eficacia diagnóstica del estudio de contactos de enfermos tuberculosos en un distrito urbano de alta prevalencia. Revista Clinica Espanola, 200(8), 412-419.

Eficacia diagnóstica del estudio de contactos de enfermos tuberculosos en un distrito urbano de alta prevalencia. / Solsona Peiró, J.; Caylà, J. A.; Bedia, M.; Mata, C.; Claveria, J.; Estrada, M. P.; Garcia, S.; Besora, R.; Roca, D.; Miquel, B.; Altet, N.; Nadal, J.; Maldonado, J.; Fernández, A.; Alcaide, J.

In: Revista Clinica Espanola, Vol. 200, No. 8, 08.2000, p. 412-419.

Research output: Contribution to journalArticle

Solsona Peiró, J, Caylà, JA, Bedia, M, Mata, C, Claveria, J, Estrada, MP, Garcia, S, Besora, R, Roca, D, Miquel, B, Altet, N, Nadal, J, Maldonado, J, Fernández, A & Alcaide, J 2000, 'Eficacia diagnóstica del estudio de contactos de enfermos tuberculosos en un distrito urbano de alta prevalencia', Revista Clinica Espanola, vol. 200, no. 8, pp. 412-419.
Solsona Peiró J, Caylà JA, Bedia M, Mata C, Claveria J, Estrada MP et al. Eficacia diagnóstica del estudio de contactos de enfermos tuberculosos en un distrito urbano de alta prevalencia. Revista Clinica Espanola. 2000 Aug;200(8):412-419.
Solsona Peiró, J. ; Caylà, J. A. ; Bedia, M. ; Mata, C. ; Claveria, J. ; Estrada, M. P. ; Garcia, S. ; Besora, R. ; Roca, D. ; Miquel, B. ; Altet, N. ; Nadal, J. ; Maldonado, J. ; Fernández, A. ; Alcaide, J. / Eficacia diagnóstica del estudio de contactos de enfermos tuberculosos en un distrito urbano de alta prevalencia. In: Revista Clinica Espanola. 2000 ; Vol. 200, No. 8. pp. 412-419.
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abstract = "Background. The investigation of contacts (CI) is a main objective for the control of tuberculosis (TB) after therapeutic compliance. The present study was planned to determine the diagnostic effectiveness and degree of CI implementation as well as risk factors to generate new cases in a high prevalence area (163/105). Patients and methods. An analysis was made of the available data of CI in the Barcelona district of Ciutat Vella in 1997 and 1998. The odds ratio (OR) was calculated as a measure of the association with infection and tuberculosis disease with a 95{\%} confidence interval (CI) by logistic regression. Results. CI was made in 65.2{\%} of patients and 100{\%} of tuberculin-positive children. Thirty patients were diagnosed among 858 contacts of 135 tuberculosis patients (3.49{\%}) and 8 among 318 contacts of 64 primoinfected children aged less than 15 years (2.51{\%}). Prevalence of tuberculosis infection was 51.51{\%} and 46.85{\%}, respectively. The characteristics of the index case associated with new patients were drug abuse (OR: 11.16; CI: 3.0-40.9) and to be prisoner (OR: 18.7; CI: 1.5-232.9). No influence was detected regarding sputum acid-fast smears and degree of closeness except for contacts aged less than 20 years. Conclusions. CI is cost-effective in this area of high prevalence and should be performed in every TB case although priority groups are prisoners and/or drug abusers and contacts aged less than 20 years. The implementation of CI can be improved in our setting.",
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AU - Solsona Peiró, J.

AU - Caylà, J. A.

AU - Bedia, M.

AU - Mata, C.

AU - Claveria, J.

AU - Estrada, M. P.

AU - Garcia, S.

AU - Besora, R.

AU - Roca, D.

AU - Miquel, B.

AU - Altet, N.

AU - Nadal, J.

AU - Maldonado, J.

AU - Fernández, A.

AU - Alcaide, J.

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N2 - Background. The investigation of contacts (CI) is a main objective for the control of tuberculosis (TB) after therapeutic compliance. The present study was planned to determine the diagnostic effectiveness and degree of CI implementation as well as risk factors to generate new cases in a high prevalence area (163/105). Patients and methods. An analysis was made of the available data of CI in the Barcelona district of Ciutat Vella in 1997 and 1998. The odds ratio (OR) was calculated as a measure of the association with infection and tuberculosis disease with a 95% confidence interval (CI) by logistic regression. Results. CI was made in 65.2% of patients and 100% of tuberculin-positive children. Thirty patients were diagnosed among 858 contacts of 135 tuberculosis patients (3.49%) and 8 among 318 contacts of 64 primoinfected children aged less than 15 years (2.51%). Prevalence of tuberculosis infection was 51.51% and 46.85%, respectively. The characteristics of the index case associated with new patients were drug abuse (OR: 11.16; CI: 3.0-40.9) and to be prisoner (OR: 18.7; CI: 1.5-232.9). No influence was detected regarding sputum acid-fast smears and degree of closeness except for contacts aged less than 20 years. Conclusions. CI is cost-effective in this area of high prevalence and should be performed in every TB case although priority groups are prisoners and/or drug abusers and contacts aged less than 20 years. The implementation of CI can be improved in our setting.

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