Diagnostic challenges in thyroid cytopathology

Research output: Contribution to journalArticle

Abstract

Fine needle aspiration (FNA) is a long-standing modality used to obtain diagnostic material from patients with thyroid nodules. However, some common and uncommon situations exist in which diagnostic categorization of an FNA specimen is not straightforward. Diagnostically challenging thyroid lesions are typically either benign entities with cytomorphology that mimics malignancy, or malignant entities with unusual cytomorphology that causes difficulty in classification. Awareness of such diagnostic challenges can help broaden one's differential diagnosis when encountering such lesions on FNA. However, in many instances a definitive diagnosis may not be possible and providing an indeterminate diagnosis is most appropriate.

Original languageEnglish (US)
JournalDiagnostic Histopathology
DOIs
StateAccepted/In press - 2016

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Fine Needle Biopsy
Thyroid Gland
Thyroid Nodule
Differential Diagnosis
Neoplasms

Keywords

  • Fine needle aspiration
  • Papillary thyroid carcinoma
  • The Bethesda System for Reporting Thyroid Cytopathology
  • Thyroid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

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abstract = "Fine needle aspiration (FNA) is a long-standing modality used to obtain diagnostic material from patients with thyroid nodules. However, some common and uncommon situations exist in which diagnostic categorization of an FNA specimen is not straightforward. Diagnostically challenging thyroid lesions are typically either benign entities with cytomorphology that mimics malignancy, or malignant entities with unusual cytomorphology that causes difficulty in classification. Awareness of such diagnostic challenges can help broaden one's differential diagnosis when encountering such lesions on FNA. However, in many instances a definitive diagnosis may not be possible and providing an indeterminate diagnosis is most appropriate.",
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AB - Fine needle aspiration (FNA) is a long-standing modality used to obtain diagnostic material from patients with thyroid nodules. However, some common and uncommon situations exist in which diagnostic categorization of an FNA specimen is not straightforward. Diagnostically challenging thyroid lesions are typically either benign entities with cytomorphology that mimics malignancy, or malignant entities with unusual cytomorphology that causes difficulty in classification. Awareness of such diagnostic challenges can help broaden one's differential diagnosis when encountering such lesions on FNA. However, in many instances a definitive diagnosis may not be possible and providing an indeterminate diagnosis is most appropriate.

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