Abstract
A retrospective view of the critical events and advances in the development of criteria, instruments and algorithms in the diagnosis of Alzheimer's disease. The review is from the vantage point of the National Institute on Aging and its role in the development of the national infrastructure, in the US, for clinical research on dementia. The paper discusses future research needs and challenges for developing newdiagnostic armamentariumfor early and accurate detection of neurodegenerative processes of dementia in the early prodromal stages or during early mild cognitive impairments.
| Original language | English (US) |
|---|---|
| Title of host publication | Alzheimer's Disease: A Century of Scientific and Clinical Research |
| Publisher | IOS Press |
| Pages | 409-415 |
| Number of pages | 7 |
| ISBN (Print) | 9781586036195 |
| State | Published - Jul 2006 |
| Externally published | Yes |
Keywords
- Alzheimer's disease
- Biomarkers
- Dementia
- Diagnosis
- Diagnostic criteria
- Diagnostic instruments
- MCI
- Mild cognitive impairments
- National Institute on Aging
- Neuroimaging
- NIA
- NIH
ASJC Scopus subject areas
- General Neuroscience