Diagnosis and characterization of brain tumors: MR spectroscopic imaging

Research output: Chapter in Book/Report/Conference proceedingChapter


In vivo proton magnetic resonance spectroscopy (MRS) was first demonstrated to be feasible in vivo in the human brain in the mid-1980s [1], and the first example of it being applied to human brain tumors following soon after in 1989 [2]. It was already apparent from this paper that brain tumors had greatly different metabolite profiles compared to normal tissue, and that differences in spectra may exist between different brain lesions of different pathologies. Since that time, there has been steady progress in the use of MRS and the related technique of magnetic resonance spectroscopic imaging (MRSI) for the clinical evaluation of human brain tumors [3].

Original languageEnglish (US)
Title of host publicationFunctional Brain Tumor Imaging
PublisherSpringer New York
Number of pages17
ISBN (Electronic)9781441958587
ISBN (Print)1441958576, 9781441958570
StatePublished - May 1 2013

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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