Diabetic retinopathy

J. Fernando Arévalo, Andres F. Lasave, David G. Zeballos, Sergio Bonafonte-Roy

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Diabetic retinopathy remains a major threat to sight in the working-age population in the developed world. In proliferative diabetic retinopathy (PDR), the growth of new vessels is thought to occur as a result of vascular endothelial growth factor (VEGF) release into the vitreous cavity as a response to ischemia, which facilitates the process of angiogenesis and macular edema. In these patients, the introduction of new therapies, such as VEGF inhibitors, may have a beneficial effect on diabetic retinopathy including diabetic macular edema and retinal neovascularization, and these therapies could complement laser photocoagulation treatment.

Original languageEnglish (US)
Title of host publicationRetinal and Choroidal Manifestations of Selected Systemic Diseases
PublisherSpringer New York
Pages387-416
Number of pages30
ISBN (Electronic)9781461436461
ISBN (Print)9781461436454
DOIs
StatePublished - Jan 1 2013

Keywords

  • Diffuse diabetic macular edema
  • Nonproliferative diabetic retinopathy
  • Proliferative diabetic retinopathy
  • Retinal photocoagulation
  • Tractional retinal detachment
  • VEGF inhibitors
  • Vascular endothelial growth factor

ASJC Scopus subject areas

  • Medicine(all)

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