Developments in nuclear cardiology: Transition from single photon emission computed tomography to positron emission tomography/computed tomography

Martin A. Lodge, Henning Braess, Faaiza Mahmoud, Jongdae Suh, Nancy Englar, Sandra Geyser-Stoops, Jason Jenkins, Stephen L. Bacharach, Vasken Dilsizian

Research output: Contribution to journalReview article

Abstract

Recent advances in positron emission tomography (PET) instrumentation have paralleled those of multichannel computed tomography (CT) for cardiac applications. Whereas multichannel CT angiography provides information on the presence and extent of anatomical luminal narrowing of epicardial coronary arteries, stress myocardial perfusion PET provides information on the downstream functional consequences of such anatomic lesions. With the advent of hybrid PET/CT systems, such complementary information of anatomy and physiology can be realized immediately at the same imaging session. By acquiring dynamic, gated myocardial perfusion data, PET studies provide insight into impairment of regional coronary blood flow reserve and microvascular endothelial dysfunction. This paper presents recent developments in PET detector materials, acquisition modes, combined PET/CT scanners, rubidium-82 (Rb-82) gated myocardial perfusion studies and analysis methods for absolute myocardial blood flow quantification.

Original languageEnglish (US)
Pages (from-to)491-496
Number of pages6
JournalJournal of Invasive Cardiology
Volume17
Issue number9
StatePublished - Sep 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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    Lodge, M. A., Braess, H., Mahmoud, F., Suh, J., Englar, N., Geyser-Stoops, S., Jenkins, J., Bacharach, S. L., & Dilsizian, V. (2005). Developments in nuclear cardiology: Transition from single photon emission computed tomography to positron emission tomography/computed tomography. Journal of Invasive Cardiology, 17(9), 491-496.