Abstract
The nocturnal spontaneous locomotor behavior of vitamin B-6 restricted and control rats was measured using activity chambers. The results show a generalized hypoactivity in indices of horizontal and vertical activity in neonatal rats fed vitamin B-6 restricted diets during gestation and lactation. This pattern of locomotor behavior changed in the postweaning period to a gradual increase in indices of locomotor activity to a pronounced hyperkinesis in vitamin B-6 restricted young adult rats. This study suggests that long-term vitamin B-6 restriction results in damage and/or abnormal development of neuronal system(s) associated with locomotor behavior.
Original language | English (US) |
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Pages (from-to) | 857-861 |
Number of pages | 5 |
Journal | Brain Research Bulletin |
Volume | 26 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1991 |
Keywords
- Deficiency
- Development
- Hyperactivity
- Locomotor behavior
- Rats
- Vitamin B-6
ASJC Scopus subject areas
- Neuroscience(all)