Development of comprehensive disease assessment in systemic vasculitis

Oliver Flossmann, Paul Bacon, Kirsten De Groot, David Jayne, Niels Rasmussen, Philip Seo, Kerstin Westman, Raashid Luqmani

Research output: Contribution to journalArticle

Abstract

The systemic vasculites are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This article reviews and summarises the development and use of disease assessment tools for determining activity and damage in systemic vasculitis and reports ongoing initiatives for further development of disease assessment tools. A literature search was conducted using PubMed and reference lists for vasculitis, assessment, clinical trials, outcome and prognosis. The findings indicate that comprehensive disease assessment in vasculitis requires documentation of disease activity, chronic irreversible damage and impairment of function.

Original languageEnglish (US)
Pages (from-to)143-152
Number of pages10
JournalPostgraduate Medical Journal
Volume84
Issue number989
DOIs
StatePublished - Mar 2008

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Systemic Vasculitis
Vasculitis
Clinical Trials
PubMed
Documentation
Chronic Disease
Biomarkers
Morbidity
Recurrence
Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Flossmann, O., Bacon, P., De Groot, K., Jayne, D., Rasmussen, N., Seo, P., ... Luqmani, R. (2008). Development of comprehensive disease assessment in systemic vasculitis. Postgraduate Medical Journal, 84(989), 143-152. https://doi.org/10.1136/ard.2005.051078

Development of comprehensive disease assessment in systemic vasculitis. / Flossmann, Oliver; Bacon, Paul; De Groot, Kirsten; Jayne, David; Rasmussen, Niels; Seo, Philip; Westman, Kerstin; Luqmani, Raashid.

In: Postgraduate Medical Journal, Vol. 84, No. 989, 03.2008, p. 143-152.

Research output: Contribution to journalArticle

Flossmann, O, Bacon, P, De Groot, K, Jayne, D, Rasmussen, N, Seo, P, Westman, K & Luqmani, R 2008, 'Development of comprehensive disease assessment in systemic vasculitis', Postgraduate Medical Journal, vol. 84, no. 989, pp. 143-152. https://doi.org/10.1136/ard.2005.051078
Flossmann, Oliver ; Bacon, Paul ; De Groot, Kirsten ; Jayne, David ; Rasmussen, Niels ; Seo, Philip ; Westman, Kerstin ; Luqmani, Raashid. / Development of comprehensive disease assessment in systemic vasculitis. In: Postgraduate Medical Journal. 2008 ; Vol. 84, No. 989. pp. 143-152.
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