Abstract
The prevalence and growth of benign prostatic hyperplasia (BPH) in beagles as a function of age were studied. The normal prostate gland was 12 ± 3 gm in beagles 2.1‐3.0 years of age; this weight remained unchanged unless BPH developed. Histologic evidence of BPH developed at an early age with a prevalence of 16% of the dogs by the age 2 years. Fifty percent of the dogs had BPH, determined histopathologically by age 4.1‐5.0 years. The average weight of the prostate gland remained constant until after age 8 years. With age, the pathologic features of BPH changed from glandular to the complex form, with no increase in prostate weight until after 8 years. Reinitiation of growth occurred and prostate weight increased to greater than 36 gm in eight of 185 beagles older than age 8 years.
Original language | English (US) |
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Pages (from-to) | 363-373 |
Number of pages | 11 |
Journal | The Prostate |
Volume | 9 |
Issue number | 4 |
DOIs | |
State | Published - 1986 |
Externally published | Yes |
Keywords
- BPH
- aging
- canine
- complex
- development
- glandular
- normal
- prostate
ASJC Scopus subject areas
- Oncology
- Urology