This presentation will raise specific issues and explore areas that need discussion and development of mechanistically based tests in toxicology. In addition, an approach to validation will be presented that is based on fundamental principles and modeled after actual practice in other areas of methodology acceptance. Further, it is recognized that the validation process is but only one aspect of incorporation of in vitro approaches into safety- evaluation and risk assessment.
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of Toxicological Sciences|
|State||Published - Jan 1 1995|
ASJC Scopus subject areas