Development of alternative methods

Research output: Contribution to journalArticlepeer-review


This presentation will raise specific issues and explore areas that need discussion and development of mechanistically based tests in toxicology. In addition, an approach to validation will be presented that is based on fundamental principles and modeled after actual practice in other areas of methodology acceptance. Further, it is recognized that the validation process is but only one aspect of incorporation of in vitro approaches into safety- evaluation and risk assessment.

Original languageEnglish (US)
Pages (from-to)443-449
Number of pages7
JournalJournal of Toxicological Sciences
Issue number4
StatePublished - 1995

ASJC Scopus subject areas

  • Toxicology


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