Development of a foundation for a case definition of post-treatment Lyme disease syndrome

Research output: Contribution to journalArticle

Abstract

Objectives: The study objective is to demonstrate the clinical and research utility of an operationalized definition of post-treatment Lyme disease syndrome (PTLDS), as proposed by the Infectious Diseases Society of America. Methods: Seventy-four patients with confirmed erythema migrans and 14 controls were enrolled. Patient-reported symptoms and health function (SF-36) were collected pre-treatment and at follow-up visits over 6 months post-treatment. Results: Eight (11%) patients met our operationalized definition of PTLDS, which included self-reported symptoms of fatigue, widespread musculoskeletal pain or cognitive complaints, and functional impact as measured by a T score of

Original languageEnglish (US)
JournalInternational Journal of Infectious Diseases
Volume17
Issue number6
DOIs
StatePublished - Jun 2013

Fingerprint

Lyme Disease
Musculoskeletal Pain
Therapeutics
Erythema
Fatigue
Health
Research

Keywords

  • Function
  • Lyme disease
  • Measurement
  • Post-treatment Lyme disease syndrome

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

@article{6b1dc40deace424196b2f0d01d9b12ad,
title = "Development of a foundation for a case definition of post-treatment Lyme disease syndrome",
abstract = "Objectives: The study objective is to demonstrate the clinical and research utility of an operationalized definition of post-treatment Lyme disease syndrome (PTLDS), as proposed by the Infectious Diseases Society of America. Methods: Seventy-four patients with confirmed erythema migrans and 14 controls were enrolled. Patient-reported symptoms and health function (SF-36) were collected pre-treatment and at follow-up visits over 6 months post-treatment. Results: Eight (11{\%}) patients met our operationalized definition of PTLDS, which included self-reported symptoms of fatigue, widespread musculoskeletal pain or cognitive complaints, and functional impact as measured by a T score of",
keywords = "Function, Lyme disease, Measurement, Post-treatment Lyme disease syndrome",
author = "John Aucott and Crowder, {Lauren A.} and Kortte, {Kathleen Bechtold}",
year = "2013",
month = "6",
doi = "10.1016/j.ijid.2013.01.008",
language = "English (US)",
volume = "17",
journal = "International Journal of Infectious Diseases",
issn = "1201-9712",
publisher = "Elsevier",
number = "6",

}

TY - JOUR

T1 - Development of a foundation for a case definition of post-treatment Lyme disease syndrome

AU - Aucott, John

AU - Crowder, Lauren A.

AU - Kortte, Kathleen Bechtold

PY - 2013/6

Y1 - 2013/6

N2 - Objectives: The study objective is to demonstrate the clinical and research utility of an operationalized definition of post-treatment Lyme disease syndrome (PTLDS), as proposed by the Infectious Diseases Society of America. Methods: Seventy-four patients with confirmed erythema migrans and 14 controls were enrolled. Patient-reported symptoms and health function (SF-36) were collected pre-treatment and at follow-up visits over 6 months post-treatment. Results: Eight (11%) patients met our operationalized definition of PTLDS, which included self-reported symptoms of fatigue, widespread musculoskeletal pain or cognitive complaints, and functional impact as measured by a T score of

AB - Objectives: The study objective is to demonstrate the clinical and research utility of an operationalized definition of post-treatment Lyme disease syndrome (PTLDS), as proposed by the Infectious Diseases Society of America. Methods: Seventy-four patients with confirmed erythema migrans and 14 controls were enrolled. Patient-reported symptoms and health function (SF-36) were collected pre-treatment and at follow-up visits over 6 months post-treatment. Results: Eight (11%) patients met our operationalized definition of PTLDS, which included self-reported symptoms of fatigue, widespread musculoskeletal pain or cognitive complaints, and functional impact as measured by a T score of

KW - Function

KW - Lyme disease

KW - Measurement

KW - Post-treatment Lyme disease syndrome

UR - http://www.scopus.com/inward/record.url?scp=84877119363&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877119363&partnerID=8YFLogxK

U2 - 10.1016/j.ijid.2013.01.008

DO - 10.1016/j.ijid.2013.01.008

M3 - Article

VL - 17

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

SN - 1201-9712

IS - 6

ER -