TY - JOUR
T1 - Development and preliminary evaluation of an online educational video about whole-genome sequencing for research participants, patients, and the general public
AU - Sanderson, Saskia C.
AU - Suckiel, Sabrina A.
AU - Zweig, Micol
AU - Bottinger, Erwin P.
AU - Jabs, Ethylin Wang
AU - Richardson, Lynne D.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Background:As whole-genome sequencing (WGS) increases in availability, WGS educational aids are needed for research participants, patients, and the general public. Our aim was therefore to develop an accessible and scalable WGS educational aid.Methods:We engaged multiple stakeholders in an iterative process over a 1-year period culminating in the production of a novel 10-minute WGS educational animated video, "Whole Genome Sequencing and You" (https://goo.gl/HV8ezJ). We then presented the animated video to 281 online-survey respondents (the video-information group). There were also two comparison groups: a written-information group (n = 281) and a no-information group (n = 300).Results:In the video-information group, 79% reported the video was easy to understand, satisfaction scores were high (mean 4.00 on 1-5 scale, where 5 = high satisfaction), and knowledge increased significantly. There were significant differences in knowledge compared with the no-information group but few differences compared with the written-information group. Intention to receive personal results from WGS and decisional conflict in response to a hypothetical scenario did not differ between the three groups.Conclusions:The educational animated video, "Whole Genome Sequencing and You," was well received by this sample of online-survey respondents. Further work is needed to evaluate its utility as an aid to informed decision making about WGS in other populations.
AB - Background:As whole-genome sequencing (WGS) increases in availability, WGS educational aids are needed for research participants, patients, and the general public. Our aim was therefore to develop an accessible and scalable WGS educational aid.Methods:We engaged multiple stakeholders in an iterative process over a 1-year period culminating in the production of a novel 10-minute WGS educational animated video, "Whole Genome Sequencing and You" (https://goo.gl/HV8ezJ). We then presented the animated video to 281 online-survey respondents (the video-information group). There were also two comparison groups: a written-information group (n = 281) and a no-information group (n = 300).Results:In the video-information group, 79% reported the video was easy to understand, satisfaction scores were high (mean 4.00 on 1-5 scale, where 5 = high satisfaction), and knowledge increased significantly. There were significant differences in knowledge compared with the no-information group but few differences compared with the written-information group. Intention to receive personal results from WGS and decisional conflict in response to a hypothetical scenario did not differ between the three groups.Conclusions:The educational animated video, "Whole Genome Sequencing and You," was well received by this sample of online-survey respondents. Further work is needed to evaluate its utility as an aid to informed decision making about WGS in other populations.
UR - http://www.scopus.com/inward/record.url?scp=84964866092&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964866092&partnerID=8YFLogxK
U2 - 10.1038/gim.2015.118
DO - 10.1038/gim.2015.118
M3 - Article
C2 - 26334178
AN - SCOPUS:84964866092
SN - 1098-3600
VL - 18
SP - 501
EP - 512
JO - Genetics in Medicine
JF - Genetics in Medicine
IS - 5
ER -