TY - JOUR
T1 - Development and Feasibility Testing of a Critical Care EEG Monitoring Database for Standardized Clinical Reporting and Multicenter Collaborative Research
AU - Lee, Jong Woo
AU - LaRoche, Suzette
AU - Choi, Hyunmi
AU - Rodriguez Ruiz, Andres A.
AU - Fertig, Evan
AU - Politsky, Jeffrey M.
AU - Herman, Susan T.
AU - Loddenkemper, Tobias
AU - Sansevere, Arnold J.
AU - Korb, Pearce J.
AU - Abend, Nicholas S.
AU - Goldstein, Joshua L.
AU - Sinha, Saurabh R.
AU - Dombrowski, Keith E.
AU - Ritzl, Eva K.
AU - Westover, Michael B.
AU - Gavvala, Jay R.
AU - Gerard, Elizabeth E.
AU - Schmitt, Sarah E.
AU - Szaflarski, Jerzy P.
AU - Ding, Kan
AU - Haas, Kevin F.
AU - Buchsbaum, Richard
AU - Hirsch, Lawrence J.
AU - Wusthoff, Courtney J.
AU - Hopp, Jennifer L.
AU - Hahn, Cecil D.
N1 - Funding Information:
This work was supported by research infrastructure awards by the American Epilepsy Society and Epilepsy Foundation of America.
Publisher Copyright:
© 2015 by the American Clinical Neurophysiology Society.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Purpose: The rapid expansion of the use of continuous critical care electroencephalogram (cEEG) monitoring and resulting multicenter research studies through the Critical Care EEG Monitoring Research Consortium has created the need for a collaborative data sharing mechanism and repository. The authors describe the development of a research database incorporating the American Clinical Neurophysiology Society standardized terminology for critical care EEG monitoring. The database includes flexible report generation tools that allow for daily clinical use. Methods: Key clinical and research variables were incorporated into a Microsoft Access database. To assess its utility for multicenter research data collection, the authors performed a 21-center feasibility study in which each center entered data from 12 consecutive intensive care unit monitoring patients. To assess its utility as a clinical report generating tool, three large volume centers used it to generate daily clinical critical care EEG reports. Results: A total of 280 subjects were enrolled in the multicenter feasibility study. The duration of recording (median, 25.5 hours) varied significantly between the centers. The incidence of seizure (17.6%), periodic/rhythmic discharges (35.7%), and interictal epileptiform discharges (11.8%) was similar to previous studies. The database was used as a clinical reporting tool by 3 centers that entered a total of 3,144 unique patients covering 6,665 recording days. Conclusions: The Critical Care EEG Monitoring Research Consortium database has been successfully developed and implemented with a dual role as a collaborative research platform and a clinical reporting tool. It is now available for public download to be used as a clinical data repository and report generating tool.
AB - Purpose: The rapid expansion of the use of continuous critical care electroencephalogram (cEEG) monitoring and resulting multicenter research studies through the Critical Care EEG Monitoring Research Consortium has created the need for a collaborative data sharing mechanism and repository. The authors describe the development of a research database incorporating the American Clinical Neurophysiology Society standardized terminology for critical care EEG monitoring. The database includes flexible report generation tools that allow for daily clinical use. Methods: Key clinical and research variables were incorporated into a Microsoft Access database. To assess its utility for multicenter research data collection, the authors performed a 21-center feasibility study in which each center entered data from 12 consecutive intensive care unit monitoring patients. To assess its utility as a clinical report generating tool, three large volume centers used it to generate daily clinical critical care EEG reports. Results: A total of 280 subjects were enrolled in the multicenter feasibility study. The duration of recording (median, 25.5 hours) varied significantly between the centers. The incidence of seizure (17.6%), periodic/rhythmic discharges (35.7%), and interictal epileptiform discharges (11.8%) was similar to previous studies. The database was used as a clinical reporting tool by 3 centers that entered a total of 3,144 unique patients covering 6,665 recording days. Conclusions: The Critical Care EEG Monitoring Research Consortium database has been successfully developed and implemented with a dual role as a collaborative research platform and a clinical reporting tool. It is now available for public download to be used as a clinical data repository and report generating tool.
KW - Clinical reporting tool
KW - Continuous EEG monitoring
KW - Research database
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U2 - 10.1097/WNP.0000000000000230
DO - 10.1097/WNP.0000000000000230
M3 - Article
C2 - 26943901
AN - SCOPUS:84962705447
SN - 0736-0258
VL - 33
SP - 133
EP - 140
JO - Journal of Clinical Neurophysiology
JF - Journal of Clinical Neurophysiology
IS - 2
ER -