Recent data suggest that endometrial maturation correlates highly with the postovulatory day as determined by ultrasound or identification of the urinary luteinizing hormone (LH) surge. A study was performed to determine the level of correlation between two methods of endometrial biopsy (EB) interpretation. Method 1 correlated histology with the onset of the next menstrual period; method 2 correlated it with the postovulatory day relative to the LH surge. Forty EBs were analyzed. Both methods agreed that 20/40 EBs were in phase and 6/40 EBs were out of phase (greater than a two-day lag between histologic endometrial maturation and chronologic dating). Of the remaining 14 EBs, 8 were in phase by method 1 and out of phase by method 2, and 6 were out of phase by method 1 and in phase by method 2. Thus, 35% of EBs were considered in phase by one method and out of phase by the alternative method. This implies that 35% of management decisions regarding whether to repeat an EB or treat an out-of-phase EB may be influenced by the method of interpreting EBs.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Reproductive Medicine for the Obstetrician and Gynecologist|
|State||Published - Jan 1 1992|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology