Determination of serum organic acids in puppies with naturally acquired parvoviral enteritis

Germain Nappert, Elizabeth Dunphy, Dawn Ruben, F. A. Mann

Research output: Contribution to journalArticle

Abstract

The purpose of the present study was to investigate the acid-base status and the serum concentration of organic acids in puppies with naturally occurring canine parvoviral enteritis. Between July 1999 and July 2000, 25 client-owned puppies admitted to the St. Louis Animal Emergency Clinic South for treatment of enteritis caused by parvovirus infection were used in our study. Control blood samples were collected from 22 healthy puppies less than 9 months of age. Serum organic acid concentrations were quantitatively determined by HPLC. Puppies infected with parvovirus had significantly lower plasma concentrations of sodium, potassium, chloride, and bicarbonate than controls. Although serum L-lactate tended to increase in some puppies with canine parvoviral enteritis, our study demonstrated that most affected puppies developed only mild compensated metabolic acidosis. None of the affected puppies had an elevated serum D-lactate concentration at admission.

Original languageEnglish (US)
Pages (from-to)15-18
Number of pages4
JournalCanadian journal of veterinary research = Revue canadienne de recherche veterinaire
Volume66
Issue number1
StatePublished - 2002
Externally publishedYes

Fingerprint

Enteritis
puppies
enteritis
blood serum
organic acids and salts
Acids
Serum
Canidae
Lactic Acid
Protoparvovirus
Parvoviridae Infections
Parvovirus
Sodium Bicarbonate
Potassium Chloride
Acidosis
lactates
Sodium Chloride
potassium bicarbonate
Emergencies
High Pressure Liquid Chromatography

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Determination of serum organic acids in puppies with naturally acquired parvoviral enteritis. / Nappert, Germain; Dunphy, Elizabeth; Ruben, Dawn; Mann, F. A.

In: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, Vol. 66, No. 1, 2002, p. 15-18.

Research output: Contribution to journalArticle

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