Determination of Poiychlorinated Dibenzo-p-dioxins in Biological Samples by Negative Chemical Ionization Mass Spectrometry

J. R. Hass; M. D. Friesen; D. J. Harvan; C. E. Parker

doi:10.1021/ac50033a023

Determination of Poiychlorinated Dibenzo-p-dioxins in Biological Samples by Negative Chemical Ionization Mass Spectrometry

J. R. Hass, M. D. Friesen, D. J. Harvan, C. E. Parker

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Methane positive chemical ionization and electron impact are found to be as much as 1000-fold less sensitive than methane negative chemical ionization for the detection of poly-chlorodibenzo-p-dioxins. The use of oxygen with or without methane results in somewhat decreased sensitivity and increased specificity for these compounds. The application of methane negative chemical ionization mass spectrometry for the determination of dioxins in tissue and wood is discussed.

Original language	English (US)
Pages (from-to)	1474-1479
Number of pages	6
Journal	Analytical chemistry
Volume	50
Issue number	11
DOIs	https://doi.org/10.1021/ac50033a023
State	Published - Jan 1 1978

ASJC Scopus subject areas

Analytical Chemistry

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abstract = "Methane positive chemical ionization and electron impact are found to be as much as 1000-fold less sensitive than methane negative chemical ionization for the detection of poly-chlorodibenzo-p-dioxins. The use of oxygen with or without methane results in somewhat decreased sensitivity and increased specificity for these compounds. The application of methane negative chemical ionization mass spectrometry for the determination of dioxins in tissue and wood is discussed.",

author = "Hass, {J. R.} and Friesen, {M. D.} and Harvan, {D. J.} and Parker, {C. E.}",

year = "1978",

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AU - Harvan, D. J.

AU - Parker, C. E.

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N2 - Methane positive chemical ionization and electron impact are found to be as much as 1000-fold less sensitive than methane negative chemical ionization for the detection of poly-chlorodibenzo-p-dioxins. The use of oxygen with or without methane results in somewhat decreased sensitivity and increased specificity for these compounds. The application of methane negative chemical ionization mass spectrometry for the determination of dioxins in tissue and wood is discussed.

AB - Methane positive chemical ionization and electron impact are found to be as much as 1000-fold less sensitive than methane negative chemical ionization for the detection of poly-chlorodibenzo-p-dioxins. The use of oxygen with or without methane results in somewhat decreased sensitivity and increased specificity for these compounds. The application of methane negative chemical ionization mass spectrometry for the determination of dioxins in tissue and wood is discussed.

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Determination of Poiychlorinated Dibenzo-p-dioxins in Biological Samples by Negative Chemical Ionization Mass Spectrometry

Abstract

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