Determination of disk diffusion and MIC quality control guidelines for solithromycin, a novel fluoroketolide antibacterial, against neisseria gonorrhoeae

Stefan Riedel; James E. Ross; David J. Farrell; Robert K. Flamm; Ronald N. Jones

doi:10.1128/JCM.02250-15

Determination of disk diffusion and MIC quality control guidelines for solithromycin, a novel fluoroketolide antibacterial, against neisseria gonorrhoeae

Stefan Riedel, James E. Ross, David J. Farrell, Robert K. Flamm, Ronald N. Jones

School of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

This solithromycin quality control study was performed to establish quality control (QC) ranges for the N. gonorrhoeae ATCC 49226 control strain for MIC agar dilution testing (AD) and zones by disk diffusion testing (DD). The following ranges were established: AD, 0.03 to 0.25 μg/ml, and DD, 33 to 43 mm. In January 2015, the CLSI Subcommittee on Antimicrobial Susceptibility Testing approved these ranges, which will be important when evaluating solithromycin against clinical isolates of N. gonorrhoeae.

Original language	English (US)
Pages (from-to)	3888-3890
Number of pages	3
Journal	Journal of clinical microbiology
Volume	53
Issue number	12
DOIs	https://doi.org/10.1128/JCM.02250-15
State	Published - Dec 2015

ASJC Scopus subject areas

Microbiology (medical)

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title = "Determination of disk diffusion and MIC quality control guidelines for solithromycin, a novel fluoroketolide antibacterial, against neisseria gonorrhoeae",

abstract = "This solithromycin quality control study was performed to establish quality control (QC) ranges for the N. gonorrhoeae ATCC 49226 control strain for MIC agar dilution testing (AD) and zones by disk diffusion testing (DD). The following ranges were established: AD, 0.03 to 0.25 μg/ml, and DD, 33 to 43 mm. In January 2015, the CLSI Subcommittee on Antimicrobial Susceptibility Testing approved these ranges, which will be important when evaluating solithromycin against clinical isolates of N. gonorrhoeae.",

author = "Stefan Riedel and Ross, {James E.} and Farrell, {David J.} and Flamm, {Robert K.} and Jones, {Ronald N.}",

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AU - Ross, James E.

AU - Farrell, David J.

AU - Flamm, Robert K.

AU - Jones, Ronald N.

PY - 2015/12

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AB - This solithromycin quality control study was performed to establish quality control (QC) ranges for the N. gonorrhoeae ATCC 49226 control strain for MIC agar dilution testing (AD) and zones by disk diffusion testing (DD). The following ranges were established: AD, 0.03 to 0.25 μg/ml, and DD, 33 to 43 mm. In January 2015, the CLSI Subcommittee on Antimicrobial Susceptibility Testing approved these ranges, which will be important when evaluating solithromycin against clinical isolates of N. gonorrhoeae.

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Determination of disk diffusion and MIC quality control guidelines for solithromycin, a novel fluoroketolide antibacterial, against neisseria gonorrhoeae

Abstract

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