Determination of bone structural parameters from multiple projection DXA images

T. S. Spisz, T. J. Beck, H. S. Feldmesser, M. H. Chen, T. C. Magee, Paul R. Bade, H. K. Charles

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To more precisely measure and monitor bone health, The Johns Hopkins University Applied Physics Lab and School of Medicine have developed the Advanced Multiple Projection Dual-Energy X-Ray Absorptiometry (AMPDXA) scanner. This system provides improvements over conventional DXA scanners in image resolution and multiple projection capability. These improvements allow us to determine structural information about the bone in addition to the standard bone mineral density (BMD) measurements. Algorithms and software were developed to process data acquired from the AMPDXA scanner and to determine important structural parameters, such as the center of mass axis in three dimensions and cross-sectional moments of inertia. The analysis operates on three projections about 15 degrees apart, calculates BMD for each projection, and then combines the data into a three dimensional coordinate system. By knowing the patient position in three dimensions, bone structural parameters are calculated more precisely. Using repeated testing of cadaver bones, the precision of determining these structural parameters is approximately the detector pixel size of 0.127 mm. Data on artificial bone cylinders indicate accuracy of about 3%. Comparisons between bone structural parameters derived from AMPDXA and CT scans show very similar results.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsA.A. Amini, A. Mandura
Pages730-741
Number of pages12
Volume5369
DOIs
StatePublished - 2004
EventMedical Imaging 2004: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: Feb 15 2004Feb 17 2004

Other

OtherMedical Imaging 2004: Physiology, Function, and Structure from Medical Images
CountryUnited States
CitySan Diego, CA
Period2/15/042/17/04

Fingerprint

bones
Bone
projection
scanners
X rays
Minerals
minerals
x rays
Computerized tomography
image resolution
moments of inertia
Image resolution
medicine
Medicine
health
center of mass
energy
monitors
Physics
Pixels

Keywords

  • Bone mass density
  • Center of mass
  • Dual x-ray absorptiometry
  • Image processing
  • Microgravity-induced bone loss
  • Osteoporosis

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Spisz, T. S., Beck, T. J., Feldmesser, H. S., Chen, M. H., Magee, T. C., Bade, P. R., & Charles, H. K. (2004). Determination of bone structural parameters from multiple projection DXA images. In A. A. Amini, & A. Mandura (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5369, pp. 730-741) https://doi.org/10.1117/12.535361

Determination of bone structural parameters from multiple projection DXA images. / Spisz, T. S.; Beck, T. J.; Feldmesser, H. S.; Chen, M. H.; Magee, T. C.; Bade, Paul R.; Charles, H. K.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / A.A. Amini; A. Mandura. Vol. 5369 2004. p. 730-741.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Spisz, TS, Beck, TJ, Feldmesser, HS, Chen, MH, Magee, TC, Bade, PR & Charles, HK 2004, Determination of bone structural parameters from multiple projection DXA images. in AA Amini & A Mandura (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5369, pp. 730-741, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, San Diego, CA, United States, 2/15/04. https://doi.org/10.1117/12.535361
Spisz TS, Beck TJ, Feldmesser HS, Chen MH, Magee TC, Bade PR et al. Determination of bone structural parameters from multiple projection DXA images. In Amini AA, Mandura A, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5369. 2004. p. 730-741 https://doi.org/10.1117/12.535361
Spisz, T. S. ; Beck, T. J. ; Feldmesser, H. S. ; Chen, M. H. ; Magee, T. C. ; Bade, Paul R. ; Charles, H. K. / Determination of bone structural parameters from multiple projection DXA images. Proceedings of SPIE - The International Society for Optical Engineering. editor / A.A. Amini ; A. Mandura. Vol. 5369 2004. pp. 730-741
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