Abstract
We evaluated quantitative real-time PCR to establish the diagnosis of rotavirus gastroenteritis in a high-disease-burden population in Malawi using enzyme immunoassay as the gold standard diagnostic test. In 146 children with acute gastroenteritis and 65 asymptomatic children, we defined a cutoff point in the threshold cycle value (26.7) that predicts rotavirus-attributable gastroenteritis in this population. These data will inform the evaluation of direct and indirect rotavirus vaccine effects in Africa.
Original language | English (US) |
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Pages (from-to) | 1951-1954 |
Number of pages | 4 |
Journal | Journal of clinical microbiology |
Volume | 53 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2015 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology (medical)