Determinants of response to eucapneic hyperventilation with cold air in a population-based study

I. B. Tager, S. T. Weiss, A. Munoz, C. Welty, F. E. Speizer

Research output: Contribution to journalArticle

Abstract

A population-based, epidemiologic investigation conducted in children, adolescents, and young adults analyzed the response to eucapneic hyperventilation with cold air as a continuous variable to better define factors that influence the expression of bronchial responsiveness. Among respiratory illness/symptom variables, only the report of asthma or persistent wheeze in the previous year and the report of a respiratory illness that led to activity restriction were significantly associated with response to cold air. Furthermore, a low, prechallenge FEF25-75/FVC ratio was a significant predictor of response, especially among those subjects who reported a respiratory illness that led to activity restriction. This relationship was not observed for a low prechallenge FEF25-75.

Original languageEnglish (US)
Pages (from-to)502-508
Number of pages7
JournalAmerican Review of Respiratory Disease
Volume134
Issue number3
StatePublished - Nov 19 1986
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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