Determinants of outcomes of acute kidney injury: Clinical predictors and beyond

Emaad M. Abdel-Rahman, Faruk Turgut, Jitendra K. Gautam, Samir C. Gautam

Research output: Contribution to journalReview articlepeer-review


Acute kidney injury (AKI) is a common clinical syndrome characterized by rapid impairment of kidney function. The incidence of AKI and its severe form AKI requiring dialysis (AKI-D) has been increasing over the years. AKI etiology may be multifactorial and is substantially associated with increased morbidity and mortality. The outcome of AKI-D can vary from partial or complete recovery to transitioning to chronic kidney disease, end stage kidney disease, or even death. Predicting outcomes of patients with AKI is crucial as it may allow clinicians to guide policy regarding adequate management of this problem and offer the best long-term options to their patients in advance. In this manuscript, we will review the current evidence regarding the determinants of AKI outcomes, focusing on AKI-D.

Original languageEnglish (US)
Article number1175
Pages (from-to)1-15
Number of pages15
JournalJournal of Clinical Medicine
Issue number6
StatePublished - Mar 2 2021


  • Acute kidney injury
  • Biomarkers
  • Mortality
  • Recovery

ASJC Scopus subject areas

  • Medicine(all)


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