Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT

Donald L. Budenz, Douglas R. Anderson, Rohit Varma, Joel Schuman, Louis Cantor, Jonathan Savell, David S. Greenfield, Vincent Michael Patella, Harry A Quigley, James Tielsch

Research output: Contribution to journalArticle

Abstract

Purpose: To determine the effects of age, optic disc area, ethnicity, eye, gender, and axial length on the retinal nerve fiber layer (RNFL) in the normal human eye as measured by Stratus OCT (optical coherence tomography). Design: Cross-sectional observational study. Participants: Three hundred twenty-eight normal subjects 18 to 85 years old. Methods: Peripapillary Fast RNFL scans performed by Stratus OCT with a nominal diameter of 3.46 mm centered on the optic disc were performed on one randomly selected eye of each subject. Main Outcome Measures: Linear regression analysis of the effects of age, ethnicity, gender, eye, axial length, and optic disc area on peripapillary RNFL thickness. Results: The mean RNFL thickness for the entire population was 100.1 μm (standard deviation, 11.6). Thinner RNFL measurements were associated with older age (P

Original languageEnglish (US)
Pages (from-to)1046-1052
Number of pages7
JournalOphthalmology
Volume114
Issue number6
DOIs
StatePublished - Jun 2007

Fingerprint

Optical Coherence Tomography
Nerve Fibers
Optic Disk
Eye Axial Length
Observational Studies
Linear Models
Cross-Sectional Studies
Regression Analysis
Outcome Assessment (Health Care)
Population

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Budenz, D. L., Anderson, D. R., Varma, R., Schuman, J., Cantor, L., Savell, J., ... Tielsch, J. (2007). Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT. Ophthalmology, 114(6), 1046-1052. https://doi.org/10.1016/j.ophtha.2006.08.046

Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT. / Budenz, Donald L.; Anderson, Douglas R.; Varma, Rohit; Schuman, Joel; Cantor, Louis; Savell, Jonathan; Greenfield, David S.; Patella, Vincent Michael; Quigley, Harry A; Tielsch, James.

In: Ophthalmology, Vol. 114, No. 6, 06.2007, p. 1046-1052.

Research output: Contribution to journalArticle

Budenz, DL, Anderson, DR, Varma, R, Schuman, J, Cantor, L, Savell, J, Greenfield, DS, Patella, VM, Quigley, HA & Tielsch, J 2007, 'Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT', Ophthalmology, vol. 114, no. 6, pp. 1046-1052. https://doi.org/10.1016/j.ophtha.2006.08.046
Budenz DL, Anderson DR, Varma R, Schuman J, Cantor L, Savell J et al. Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT. Ophthalmology. 2007 Jun;114(6):1046-1052. https://doi.org/10.1016/j.ophtha.2006.08.046
Budenz, Donald L. ; Anderson, Douglas R. ; Varma, Rohit ; Schuman, Joel ; Cantor, Louis ; Savell, Jonathan ; Greenfield, David S. ; Patella, Vincent Michael ; Quigley, Harry A ; Tielsch, James. / Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT. In: Ophthalmology. 2007 ; Vol. 114, No. 6. pp. 1046-1052.
@article{5a17bb03103041fd8ca552f6f97ed4be,
title = "Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT",
abstract = "Purpose: To determine the effects of age, optic disc area, ethnicity, eye, gender, and axial length on the retinal nerve fiber layer (RNFL) in the normal human eye as measured by Stratus OCT (optical coherence tomography). Design: Cross-sectional observational study. Participants: Three hundred twenty-eight normal subjects 18 to 85 years old. Methods: Peripapillary Fast RNFL scans performed by Stratus OCT with a nominal diameter of 3.46 mm centered on the optic disc were performed on one randomly selected eye of each subject. Main Outcome Measures: Linear regression analysis of the effects of age, ethnicity, gender, eye, axial length, and optic disc area on peripapillary RNFL thickness. Results: The mean RNFL thickness for the entire population was 100.1 μm (standard deviation, 11.6). Thinner RNFL measurements were associated with older age (P",
author = "Budenz, {Donald L.} and Anderson, {Douglas R.} and Rohit Varma and Joel Schuman and Louis Cantor and Jonathan Savell and Greenfield, {David S.} and Patella, {Vincent Michael} and Quigley, {Harry A} and James Tielsch",
year = "2007",
month = "6",
doi = "10.1016/j.ophtha.2006.08.046",
language = "English (US)",
volume = "114",
pages = "1046--1052",
journal = "Ophthalmology",
issn = "0161-6420",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT

AU - Budenz, Donald L.

AU - Anderson, Douglas R.

AU - Varma, Rohit

AU - Schuman, Joel

AU - Cantor, Louis

AU - Savell, Jonathan

AU - Greenfield, David S.

AU - Patella, Vincent Michael

AU - Quigley, Harry A

AU - Tielsch, James

PY - 2007/6

Y1 - 2007/6

N2 - Purpose: To determine the effects of age, optic disc area, ethnicity, eye, gender, and axial length on the retinal nerve fiber layer (RNFL) in the normal human eye as measured by Stratus OCT (optical coherence tomography). Design: Cross-sectional observational study. Participants: Three hundred twenty-eight normal subjects 18 to 85 years old. Methods: Peripapillary Fast RNFL scans performed by Stratus OCT with a nominal diameter of 3.46 mm centered on the optic disc were performed on one randomly selected eye of each subject. Main Outcome Measures: Linear regression analysis of the effects of age, ethnicity, gender, eye, axial length, and optic disc area on peripapillary RNFL thickness. Results: The mean RNFL thickness for the entire population was 100.1 μm (standard deviation, 11.6). Thinner RNFL measurements were associated with older age (P

AB - Purpose: To determine the effects of age, optic disc area, ethnicity, eye, gender, and axial length on the retinal nerve fiber layer (RNFL) in the normal human eye as measured by Stratus OCT (optical coherence tomography). Design: Cross-sectional observational study. Participants: Three hundred twenty-eight normal subjects 18 to 85 years old. Methods: Peripapillary Fast RNFL scans performed by Stratus OCT with a nominal diameter of 3.46 mm centered on the optic disc were performed on one randomly selected eye of each subject. Main Outcome Measures: Linear regression analysis of the effects of age, ethnicity, gender, eye, axial length, and optic disc area on peripapillary RNFL thickness. Results: The mean RNFL thickness for the entire population was 100.1 μm (standard deviation, 11.6). Thinner RNFL measurements were associated with older age (P

UR - http://www.scopus.com/inward/record.url?scp=34249671717&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249671717&partnerID=8YFLogxK

U2 - 10.1016/j.ophtha.2006.08.046

DO - 10.1016/j.ophtha.2006.08.046

M3 - Article

C2 - 17210181

AN - SCOPUS:34249671717

VL - 114

SP - 1046

EP - 1052

JO - Ophthalmology

JF - Ophthalmology

SN - 0161-6420

IS - 6

ER -