TY - JOUR
T1 - Determinants of behavioral and psychological symptoms of dementia
T2 - A scoping review of the evidence
AU - Kolanowski, Ann
AU - Boltz, Marie
AU - Galik, Elizabeth
AU - Gitlin, Laura N.
AU - Kales, Helen C.
AU - Resnick, Barbara
AU - Van Haitsma, Kimberly S.
AU - Knehans, Amy
AU - Sutterlin, Jane E.
AU - Sefcik, Justine S.
AU - Liu, Wen
AU - Petrovsky, Darina V.
AU - Massimo, Lauren
AU - Gilmore-Bykovskyi, Andrea
AU - MacAndrew, Margaret
AU - Brewster, Glenna
AU - Nalls, Vycki
AU - Jao, Ying Ling
AU - Duffort, Naomi
AU - Scerpella, Danny
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2017/9
Y1 - 2017/9
N2 - Background Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases. Purpose In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis? Method An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized. Discussion Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication. Conclusion Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.
AB - Background Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases. Purpose In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis? Method An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized. Discussion Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication. Conclusion Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.
KW - Behavioral and psychological symptoms of dementia
KW - Determinants
KW - Scoping review
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U2 - 10.1016/j.outlook.2017.06.006
DO - 10.1016/j.outlook.2017.06.006
M3 - Article
C2 - 28826872
AN - SCOPUS:85027554145
SN - 0029-6554
VL - 65
SP - 515
EP - 529
JO - Nursing outlook
JF - Nursing outlook
IS - 5
ER -