Detection of Uveal Melanoma by Multiplex Immunoassays of Serum Biomarkers

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Multiplex immunoassays simultaneously measure multiple analytes in a single sample providing quantitative data via parallel analyses, which is especially suitable for serum biomarker verification and validation. Multiplex immunoassays demonstrate several advantages over traditional enzyme-linked immunosorbent assays such as increasing productivity, conserving critical reagents and samples, and delivering results quickly. Here we describe the detection of uveal melanoma by magnetic bead-based multiplex immunoassays of serum biomarkers. The biomarker panels evaluated by multiplex immunoassays with high analytical performance demonstrated potential complementary values in detection of uveal melanoma.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages447-459
Number of pages13
DOIs
StatePublished - 2021

Publication series

NameMethods in Molecular Biology
Volume2265
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Biomarker
  • Immunoassay
  • Multiplex
  • Serum
  • Uveal melanoma

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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