Detection of type-specific antibodies to HSV-1 and HSV-2: Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA

Amelia W. Maters, Christina V. Wright, Maria Teresa Lee, Greta Schwichtenberg, Barbara Detrick

Research output: Contribution to journalArticle

Abstract

Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON® HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6% (HSV-1) and 100% (HSV-2). The LIAISON® methodology has several advantages.

Original languageEnglish (US)
Pages (from-to)273-274
Number of pages2
JournalDiagnostic Microbiology and Infectious Disease
Volume73
Issue number3
DOIs
StatePublished - Jul 2012

Fingerprint

Human Herpesvirus 2
Human Herpesvirus 1
Luminescence
Immunoassay
Enzyme-Linked Immunosorbent Assay
Antibodies
Serologic Tests
Simplexvirus
Sexually Transmitted Diseases

Keywords

  • Chemiluminescence
  • ELISA
  • HSV-1
  • HSV-2
  • Serology

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Detection of type-specific antibodies to HSV-1 and HSV-2 : Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA. / Maters, Amelia W.; Wright, Christina V.; Lee, Maria Teresa; Schwichtenberg, Greta; Detrick, Barbara.

In: Diagnostic Microbiology and Infectious Disease, Vol. 73, No. 3, 07.2012, p. 273-274.

Research output: Contribution to journalArticle

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