Detection of high-risk young adults and women by coronary calcium and national cholesterol education program panel III guidelines

Khurram Nasir, Erin Donnelly Michos, Roger S Blumenthal, Paolo Raggi

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: The purpose of this study was to investigate the classification of cardiovascular risk in young individuals and women according to the National Cholesterol Education Program (NCEP) guidelines across a continuum of coronary calcium scores (CCS). BACKGROUND: Current NCEP guidelines might underestimate cardiovascular risk in young individuals and women. METHODS: The study population consisted of 1,611 asymptomatic individuals (67% men, mean age: 53 ± 10 years) who presented to a single electron beam tomography facility for coronary artery calcium screening. Participants were categorized into low-risk (n = 738, 46%), intermediate-risk (n = 583, 36%), moderately high-risk (n = 263, 16%), and high-risk (n = 27, 2%) according to the NCEP Panel III guidelines. RESULTS: Absence of calcium, CCS of 0 to 99 (mild), 100 to 399 (moderate), and

Original languageEnglish (US)
Pages (from-to)1931-1936
Number of pages6
JournalJournal of the American College of Cardiology
Volume46
Issue number10
DOIs
StatePublished - Nov 15 2005

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Young Adult
Cholesterol
Guidelines
Calcium
Education
X Ray Computed Tomography
Coronary Vessels
Population

ASJC Scopus subject areas

  • Nursing(all)

Cite this

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title = "Detection of high-risk young adults and women by coronary calcium and national cholesterol education program panel III guidelines",
abstract = "OBJECTIVES: The purpose of this study was to investigate the classification of cardiovascular risk in young individuals and women according to the National Cholesterol Education Program (NCEP) guidelines across a continuum of coronary calcium scores (CCS). BACKGROUND: Current NCEP guidelines might underestimate cardiovascular risk in young individuals and women. METHODS: The study population consisted of 1,611 asymptomatic individuals (67{\%} men, mean age: 53 ± 10 years) who presented to a single electron beam tomography facility for coronary artery calcium screening. Participants were categorized into low-risk (n = 738, 46{\%}), intermediate-risk (n = 583, 36{\%}), moderately high-risk (n = 263, 16{\%}), and high-risk (n = 27, 2{\%}) according to the NCEP Panel III guidelines. RESULTS: Absence of calcium, CCS of 0 to 99 (mild), 100 to 399 (moderate), and",
author = "Khurram Nasir and Michos, {Erin Donnelly} and Blumenthal, {Roger S} and Paolo Raggi",
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AU - Raggi, Paolo

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AB - OBJECTIVES: The purpose of this study was to investigate the classification of cardiovascular risk in young individuals and women according to the National Cholesterol Education Program (NCEP) guidelines across a continuum of coronary calcium scores (CCS). BACKGROUND: Current NCEP guidelines might underestimate cardiovascular risk in young individuals and women. METHODS: The study population consisted of 1,611 asymptomatic individuals (67% men, mean age: 53 ± 10 years) who presented to a single electron beam tomography facility for coronary artery calcium screening. Participants were categorized into low-risk (n = 738, 46%), intermediate-risk (n = 583, 36%), moderately high-risk (n = 263, 16%), and high-risk (n = 27, 2%) according to the NCEP Panel III guidelines. RESULTS: Absence of calcium, CCS of 0 to 99 (mild), 100 to 399 (moderate), and

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